|
1
|
EcoR1 Capital
San Francisco,
California
|
$179M
|
+$55.6M
|
+1,787,112
|
+54%
|
|
|
2
|
|
$147M
|
+$5.11M
|
+164,232
|
+4%
|
|
|
3
|
Alphabet Inc
Mountain View,
California
|
$143M
|
-$16M
|
-513,343
|
-11%
|
|
|
4
|
PFM Health Sciences
San Francisco,
California
|
$120M
|
-$2.09M
|
-67,250
|
-2%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$113M
|
+$13.4M
|
+432,000
|
+15%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$108M
|
–
|
–
|
–
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$86M
|
+$1.15K
|
+37
|
+0%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$81.3M
|
-$11M
|
-354,071
|
-13%
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$72.7M
|
–
|
–
|
–
|
|
|
10
|
Invus Financial Advisors
New York
|
$64.2M
|
–
|
–
|
–
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
$59.2M
|
+$1.11M
|
+35,545
|
+2%
|
|
|
12
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$52.3M
|
+$46.7M
|
+1,501,228
|
New
|
|
|
13
|
Franklin Resources
San Mateo,
California
|
$50.8M
|
+$18.1M
|
+581,311
|
+66%
|
|
|
14
|
Octagon Capital Advisors
New York
|
$33.8M
|
+$6.54M
|
+210,000
|
+28%
|
|
|
15
|
BNP Paribas Asset Management
Paris,
France
|
$27.4M
|
+$14.7M
|
+473,310
|
+152%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$27.3M
|
+$362K
|
+11,622
|
+2%
|
|
|
17
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$25.8M
|
+$2.02M
|
+64,750
|
+10%
|
|
|
18
|
TimesSquare Capital Management
New York
|
$22.7M
|
-$1.1M
|
-35,300
|
-5%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$22.3M
|
-$870K
|
-27,949
|
-4%
|
|
|
20
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$16.1M
|
-$44.1K
|
-1,418
|
-0.3%
|
|
|
21
|
Bain Capital Public Equity Management II
Boston,
Massachusetts
|
$15.9M
|
+$14.2M
|
+454,863
|
New
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$12.4M
|
+$332K
|
+10,682
|
+3%
|
|
|
23
|
Ameriprise
Minneapolis,
Minnesota
|
$10.4M
|
–
|
–
|
–
|
|
|
24
|
Two Sigma Advisers
New York
|
$10.2M
|
-$2.65M
|
-85,200
|
-23%
|
|
|
25
|
Gilder Gagnon Howe & Co
New York
|
$10.1M
|
-$189K
|
-6,085
|
-2%
|
|
