|
1
|
Alphabet Inc
Mountain View,
California
|
$51M
|
–
|
–
|
–
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$36.1M
|
–
|
–
|
–
|
|
|
3
|
|
$35.8M
|
–
|
–
|
–
|
|
|
4
|
|
$30.4M
|
+$898K
|
+106,774
|
+4%
|
|
|
5
|
Invus Financial Advisors
New York
|
$18.6M
|
+$15.5M
|
+1,842,077
|
New
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$16.9M
|
+$11.5M
|
+1,372,233
|
+457%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$14.1M
|
+$16.7K
|
+1,988
|
+0.1%
|
|
|
8
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$7.75M
|
–
|
–
|
–
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$7.37M
|
-$207K
|
-24,600
|
-3%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$6.47M
|
+$195K
|
+23,221
|
+4%
|
|
|
11
|
|
$4.73M
|
-$362K
|
-43,000
|
-8%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$3.99M
|
+$83.3K
|
+9,907
|
+3%
|
|
|
13
|
Northern Trust
Chicago,
Illinois
|
$3.91M
|
+$194K
|
+23,045
|
+6%
|
|
|
14
|
Aisling Capital Management
New York
|
$3.37M
|
–
|
–
|
–
|
|
|
15
|
Janus Henderson Group
London,
|
$2.99M
|
-$1.72M
|
-204,654
|
-41%
|
|
|
16
|
Renaissance Technologies
New York
|
$2.19M
|
+$642K
|
+76,400
|
+54%
|
|
|
17
|
Charles Schwab
San Francisco,
California
|
$1.94M
|
+$17.5K
|
+2,078
|
+1%
|
|
|
18
|
Dimensional Fund Advisors
Austin,
Texas
|
$1.91M
|
+$1.01M
|
+120,656
|
+177%
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$1.88M
|
+$384K
|
+45,707
|
+33%
|
|
|
20
|
Millennium Management
New York
|
$1.52M
|
-$316K
|
-37,550
|
-20%
|
|
|
21
|
Bank of New York Mellon
New York
|
$1.26M
|
+$1.19K
|
+141
|
+0.1%
|
|
|
22
|
Two Sigma Investments
New York
|
$1.26M
|
+$775K
|
+92,123
|
+280%
|
|
|
23
|
|
$1.24M
|
+$244K
|
+28,982
|
+31%
|
|
|
24
|
Baker Bros. Advisors
New York
|
$1.23M
|
–
|
–
|
–
|
|
|
25
|
Platinum Investment Management
Sydney Australia 2000,
Australia
|
$1.05M
|
-$279K
|
-33,153
|
-24%
|
|
