|
1
|
EcoR1 Capital
San Francisco,
California
|
$224M
|
+$15.6M
|
+400,999
|
+8%
|
|
|
2
|
|
$167M
|
-$2.83M
|
-73,031
|
-2%
|
|
|
3
|
PFM Health Sciences
San Francisco,
California
|
$139M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$139M
|
+$37.2M
|
+959,857
|
+39%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$138M
|
+$6.53M
|
+168,245
|
+5%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$129M
|
+$3.97M
|
+102,231
|
+3%
|
|
|
7
|
Alphabet Inc
Mountain View,
California
|
$104M
|
-$59.6M
|
-1,537,034
|
-37%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$88.7M
|
-$5.42M
|
-139,699
|
-6%
|
|
|
9
|
Octagon Capital Advisors
New York
|
$84.8M
|
+$43.6M
|
+1,125,067
|
+116%
|
|
|
10
|
Woodline Partners
San Francisco,
California
|
$69.1M
|
+$284K
|
+7,312
|
+0.4%
|
|
|
11
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$66.7M
|
+$5.73M
|
+147,762
|
+10%
|
|
|
12
|
Invus Financial Advisors
New York
|
$65.2M
|
-$8.92M
|
-230,000
|
-12%
|
|
|
13
|
|
$58M
|
+$50.5M
|
+1,300,591
|
+972%
|
|
|
14
|
Boxer Capital
San Diego,
California
|
$58M
|
-$25.3M
|
-652,683
|
-31%
|
|
|
15
|
Franklin Resources
San Mateo,
California
|
$47.9M
|
-$10.6M
|
-273,828
|
-19%
|
|
|
16
|
TimesSquare Capital Management
New York
|
$39M
|
+$12.1M
|
+312,542
|
+48%
|
|
|
17
|
BNP Paribas Asset Management
Paris,
France
|
$34.9M
|
+$2.96M
|
+76,188
|
+10%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$31.1M
|
-$530K
|
-13,664
|
-2%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$25.3M
|
-$619K
|
-15,962
|
-2%
|
|
|
20
|
Bain Capital Public Equity Management II
Boston,
Massachusetts
|
$17.1M
|
-$1.25M
|
-32,098
|
-7%
|
|
|
21
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$15.4M
|
-$3.18M
|
-82,100
|
-18%
|
|
|
22
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$15M
|
+$14.4M
|
+370,597
|
New
|
|
|
23
|
|
$13.5M
|
+$5.43M
|
+140,031
|
+73%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$13M
|
-$1.28M
|
-33,091
|
-9%
|
|
|
25
|
Gilder Gagnon Howe & Co
New York
|
$11.8M
|
+$64.6K
|
+1,665
|
+0.6%
|
|
