|
1
|
Alphabet Inc
Mountain View,
California
|
$133M
|
-$11.4M
|
-326,438
|
-6%
|
|
|
2
|
PFM Health Sciences
San Francisco,
California
|
$98.2M
|
+$4.34M
|
+124,800
|
+4%
|
|
|
3
|
|
$95.3M
|
+$4.82M
|
+138,555
|
+4%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$70.9M
|
+$6.17M
|
+177,225
|
+8%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$62.7M
|
–
|
–
|
–
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$61.7M
|
–
|
–
|
–
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$60.8M
|
+$11.9M
|
+342,539
|
+19%
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$58.5M
|
–
|
–
|
–
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$52.7M
|
-$30.5M
|
-876,100
|
-32%
|
|
|
10
|
Invus Financial Advisors
New York
|
$51.7M
|
–
|
–
|
–
|
|
|
11
|
Victory Capital Management
San Antonio,
Texas
|
$43M
|
+$13.8M
|
+397,786
|
+35%
|
|
|
12
|
Ameriprise
Minneapolis,
Minnesota
|
$38.5M
|
-$209K
|
-5,998
|
-0.4%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$34.8M
|
+$43.1M
|
+1,237,730
|
New
|
|
|
14
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$24.1M
|
-$67.9K
|
-1,950
|
-0.2%
|
|
|
15
|
Franklin Resources
San Mateo,
California
|
$22.3M
|
+$2.25M
|
+64,800
|
+9%
|
|
|
16
|
TimesSquare Capital Management
New York
|
$20.2M
|
-$3.75M
|
-107,730
|
-13%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$20M
|
+$2.28M
|
+65,431
|
+10%
|
|
|
18
|
|
$16.3M
|
-$6.18M
|
-177,712
|
-23%
|
|
|
19
|
|
$15.7M
|
-$349K
|
-10,024
|
-2%
|
|
|
20
|
HealthCor Management
New York
|
$15.1M
|
+$18.7M
|
+536,970
|
New
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$14.1M
|
-$1.21M
|
-34,719
|
-6%
|
|
|
22
|
Two Sigma Advisers
New York
|
$13.1M
|
-$860K
|
-24,700
|
-5%
|
|
|
23
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$13M
|
+$36K
|
+1,034
|
+0.2%
|
|
|
24
|
Octagon Capital Advisors
New York
|
$11.2M
|
+$3.48M
|
+100,000
|
+33%
|
|
|
25
|
|
$10.6M
|
-$4.15M
|
-119,119
|
-24%
|
|
