Two Sigma Advisers
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Two Sigma Advisers’s Arcus Biosciences RCUS Stock Holding History

Two Sigma Advisers’s Portfolio RCUS Stock Details RCUS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-285,400
Closed -$3.88M – 2568
2025
Q3 		$3.88M Sell
285,400
-10,400
-4% -$108K 0.01% 836
2025
Q2 		$2.41M Buy
295,800
+171,700
+138% +$1.47M ﹤0.01% 1028
2025
Q1 		$974K Buy
124,100
+65,300
+111% +$757K ﹤0.01% 1484
2024
Q4 		$876K Buy
58,800
+15,500
+36% +$253K ﹤0.01% 1526
2024
Q3 		$662K Buy
43,300
+5,200
+14% +$82K ﹤0.01% 1594
2024
Q2 		$580K Sell
38,100
-12,700
-25% -$205K ﹤0.01% 1815
2024
Q1 		$959K Buy
50,800
+17,200
+51% +$297K ﹤0.01% 1598
2023
Q4 		$642K Sell
33,600
-2,700
-7% -$43.2K ﹤0.01% 1823
2023
Q3 		$652K Sell
36,300
-1,300
-3% -$26.1K ﹤0.01% 1694
2023
Q2 		$764K Sell
37,600
-77,800
-67% -$1.48M ﹤0.01% 1646
2023
Q1 		$2.1M Sell
115,400
-56,900
-33% -$1.09M 0.01% 1249
2022
Q4 		$3.56M Sell
172,300
-2,500
-1% -$68.8K 0.01% 924
2022
Q3 		$4.57M Buy
174,800
+40,900
+31% +$1.08M 0.01% 775
2022
Q2 		$3.39M Sell
133,900
-20,900
-14% -$512K 0.01% 939
2022
Q1 		$4.88M Sell
154,800
-121,200
-44% -$4.06M 0.01% 807
2021
Q4 		$11.2M Sell
276,000
-15,300
-5% -$593K 0.03% 472
2021
Q3 		$10.2M Sell
291,300
-85,200
-23% -$2.65M 0.03% 514
2021
Q2 		$10.3M Sell
376,500
-89,900
-19% -$2.57M 0.03% 549
2021
Q1 		$13.1M Sell
466,400
-24,700
-5% -$860K 0.04% 476
2020
Q4 		$12.7M Sell
491,100
-55,500
-10% -$1.34M 0.03% 485
2020
Q3 		$9.37M Buy
546,600
+294,500
+117% +$6.58M 0.03% 552
2020
Q2 		$6.24M Buy
252,100
+177,900
+240% +$4.8M 0.02% 719
2020
Q1 		$1.03M Buy
74,200
+900
+1% +$11.2K ﹤0.01% 1474
2019
Q4 		$740K Buy
+73,300
New +$616K ﹤0.01% 1699

Other funds holding RCUS

GS
Gilead Sciences Foster City, California $2.12B AUM 143.53% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
SCM
Suvretta Capital Management New York $3.92B AUM 86.67% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return

Two Sigma Advisers's RCUS Position: Q4 2025 in Review

Two Sigma Advisers sold out of Arcus Biosciences (RCUS) in Q4 2025, closing a stake of 285,400 shares — an estimated $3.88M sold.

Two Sigma Advisers first reported a position in RCUS in Q4 2019 and held it in 24 quarters. The position peaked at $13.1M in Q1 2021. 209 funds tracked by Wall St. Rank hold RCUS as of Q4 2025.

  • Two Sigma Advisers reported no remaining Arcus Biosciences position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Advisers sold 285,400 Arcus Biosciences shares in Q4 2025, an estimated $3.88M.
  • Two Sigma Advisers first reported a position in Arcus Biosciences in Q4 2019 and held it in 24 quarters.
  • Two Sigma Advisers's Arcus Biosciences position peaked at $13.1M in Q1 2021.
  • 209 funds tracked by Wall St. Rank held Arcus Biosciences as of Q4 2025.

Based on Two Sigma Advisers's 13F filing for Q4 2025, filed 17 Feb 2026.