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Arcus Biosciences

209 hedge funds and large institutions have $2.89B invested in Arcus Biosciences in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 95 increasing their positions, 38 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,666% more call options, than puts

Call options by funds: $92.8M | Put options by funds: $5.26M

150% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 38

112% more capital invested

Capital invested by funds: $1.37B → $2.89B (+$1.53B)

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

78% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 27

17.94% more ownership

Funds ownership: 94.53%112.48% (+18%)

10% more funds holding

Funds holding: 190209 (+19)

Holders
209
Holders Change
+19
Holders Change %
+10%
% of All Funds
2.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
48
Increased
95
Reduced
38
Closed
27
Calls
$92.8M
Puts
$5.26M
Net Calls
+$87.6M
Net Calls Change
+$43.6M
Name Holding Trade Value Shares
Change
Change in
Stake
GS
1
Gilead Sciences
California
$749M
BlackRock
2
BlackRock
New York
$357M +$65M +3,187,025 +27%
Vanguard Group
3
Vanguard Group
Pennsylvania
$190M +$27.2M +1,333,421 +20%
SCM
4
Suvretta Capital Management
New York
$124M +$30.6M +1,500,000 +41%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$124M +$79.9M +3,918,220 +309%
State Street
6
State Street
Massachusetts
$109M +$24.1M +1,182,115 +35%
WP
7
Woodline Partners
California
$89.8M +$2.12K +104 +0%
Marshall Wace
8
Marshall Wace
United Kingdom
$80.7M +$69.1M +3,387,794 New
Point72 Asset Management
9
Point72 Asset Management
Connecticut
$78.2M -$21.5M -1,052,479 -24%
SL
10
Siren LLC
Connecticut
$71.7M +$1.94M +95,000 +3%
Fisher Asset Management
11
Fisher Asset Management
Washington
$46.5M +$24.9M +1,220,635 +167%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$45.5M +$6.3M +308,936 +19%
BNP Paribas Asset Management
13
BNP Paribas Asset Management
France
$40.2M +$5.46M +267,389 +19%
SC
14
Samlyn Capital
New York
$38.2M +$32.7M +1,604,270 New
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$36.3M +$443K +21,694 +1%
Toronto Dominion Bank
16
Toronto Dominion Bank
Ontario, Canada
$35.4M +$30.3M +1,484,699 New
Morgan Stanley
17
Morgan Stanley
New York
$28.9M -$6.64M -325,334 -21%
Goldman Sachs
18
Goldman Sachs
New York
$27.8M +$4.44M +217,848 +23%
Fidelity Investments
19
Fidelity Investments
Massachusetts
$27.1M -$23.7M -1,160,843 -51%
Barclays
20
Barclays
United Kingdom
$26.5M +$19.1M +935,178 +528%
SI
21
Sofinnova Investments
California
$26.1M -$2.56M -125,558 -10%
Bank of America
22
Bank of America
North Carolina
$23.8M -$7.34M -359,963 -26%
PHP
23
Parkman Healthcare Partners
Connecticut
$23.1M +$6.45M +315,922 +48%
Charles Schwab
24
Charles Schwab
California
$23.1M +$1.98M +97,091 +11%
Jacobs Levy Equity Management
25
Jacobs Levy Equity Management
New Jersey
$22.2M -$3.88M -190,081 -17%

RCUS Hedge Fund Activity: Q4 2025 in Review

209 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q4 2025, worth a combined $2.89B — up 112% from $1.37B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new RCUS positions and 27 closed out — a net gain of 21 holders — while 95 added to existing stakes and 38 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $79.9M. The largest seller was Fidelity Investments, cutting an estimated $23.7M.

  • 209 institutional investors held Arcus Biosciences (RCUS) as of Q4 2025, up from 190 in Q3 2025.
  • Funds reported $2.89B of Arcus Biosciences stock for Q4 2025, up 112% quarter-over-quarter.
  • 48 funds opened new Arcus Biosciences positions in Q4 2025 and 27 closed out, a net change of +21 holders.
  • The largest Arcus Biosciences buyer in Q4 2025 was Wellington Management Group, an estimated $79.9M added.
  • The largest Arcus Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $23.7M sold.

Based on aggregated 13F filings for Q4 2025.