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Arcus Biosciences

190 hedge funds and large institutions have $1.37B invested in Arcus Biosciences in 2025 Q3 according to their latest regulatory filings, with 30 funds opening new positions, 65 increasing their positions, 61 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,013% more call options, than puts

Call options by funds: $46.2M | Put options by funds: $2.19M

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

69% more capital invested

Capital invested by funds: $811M → $1.37B (+$557M)

25% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 24

3% more funds holding

Funds holding: 185190 (+5)

7% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 61

0.36% more ownership

Funds ownership: 94.18%94.53% (+0.36%)

Holders
190
Holders Change
+5
Holders Change %
+2.7%
% of All Funds
2.49%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
30
Increased
65
Reduced
61
Closed
24
Calls
$46.2M
Puts
$2.19M
Net Calls
+$44M
Net Calls Change
+$19.1M
Name Holding Trade Value Shares
Change
Change in
Stake
GS
1
Gilead Sciences
California
$427M
BlackRock
2
BlackRock
New York
$161M +$3.67M +352,887 +3%
Vanguard Group
3
Vanguard Group
Pennsylvania
$90.2M +$761K +73,210 +1%
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$58.9M -$17M -1,634,185 -27%
WP
5
Woodline Partners
California
$51.3M -$2.4M -230,345 -6%
SCM
6
Suvretta Capital Management
New York
$50.2M
State Street
7
State Street
Massachusetts
$46.2M -$2.45M -235,961 -6%
SL
8
Siren LLC
Connecticut
$39.6M +$13.5M +1,300,000 +81%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$31.2M -$2.88M -277,273 -11%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$21.7M +$21.6K +2,080 +0.1%
Morgan Stanley
11
Morgan Stanley
New York
$20.9M +$689K +66,284 +5%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$20.4M -$1.64M -157,416 -9%
BNP Paribas Asset Management
13
BNP Paribas Asset Management
France
$19.3M +$252K +24,259 +2%
Bank of America
14
Bank of America
North Carolina
$18.5M +$8.97M +863,162 +173%
Wellington Management Group
15
Wellington Management Group
Massachusetts
$17.2M +$3.43M +330,268 +35%
SI
16
Sofinnova Investments
California
$16.6M +$65K +6,247 +0.5%
RCM
17
RA Capital Management
Massachusetts
$15.5M
Jacobs Levy Equity Management
18
Jacobs Levy Equity Management
New Jersey
$15.2M +$3.27M +314,757 +39%
Goldman Sachs
19
Goldman Sachs
New York
$12.9M +$3.15M +302,515 +47%
Charles Schwab
20
Charles Schwab
California
$11.8M +$982K +94,408 +12%
Fisher Asset Management
21
Fisher Asset Management
Washington
$9.92M +$6.66M +640,990 +727%
Northern Trust
22
Northern Trust
Illinois
$9.63M +$172K +16,549 +2%
PHP
23
Parkman Healthcare Partners
Connecticut
$8.88M +$552K +53,070 +9%
Millennium Management
24
Millennium Management
New York
$8.64M -$1.51M -145,144 -19%
DCM
25
DAFNA Capital Management
California
$8.54M

RCUS Hedge Fund Activity: Q3 2025 in Review

190 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q3 2025, worth a combined $1.37B — up 69% from $811M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new RCUS positions and 24 closed out — a net gain of 6 holders — while 65 added to existing stakes and 61 trimmed.

The largest buyer was Siren LLC, adding an estimated $13.5M. The largest seller was Point72 Asset Management, cutting an estimated $17M.

  • 190 institutional investors held Arcus Biosciences (RCUS) as of Q3 2025, up from 185 in Q2 2025.
  • Funds reported $1.37B of Arcus Biosciences stock for Q3 2025, up 69% quarter-over-quarter.
  • 30 funds opened new Arcus Biosciences positions in Q3 2025 and 24 closed out, a net change of +6 holders.
  • The largest Arcus Biosciences buyer in Q3 2025 was Siren LLC, an estimated $13.5M added.
  • The largest Arcus Biosciences seller in Q3 2025 was Point72 Asset Management, an estimated $17M sold.

Based on aggregated 13F filings for Q3 2025.