|
1
|
Alphabet Inc
Mountain View,
California
|
$127M
|
-$3.13M
|
-109,530
|
-2%
|
|
|
2
|
|
$111M
|
+$18.4M
|
+645,082
|
+19%
|
|
|
3
|
PFM Health Sciences
San Francisco,
California
|
$96.1M
|
–
|
–
|
–
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$91.6M
|
+$32.5M
|
+1,139,355
|
+52%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$84.9M
|
+$24.5M
|
+857,505
|
+38%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$76.8M
|
+$26.3M
|
+921,700
|
+49%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$73.7M
|
+$14.9M
|
+520,307
|
+24%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$67.7M
|
-$1.67M
|
-58,407
|
-2%
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$57.3M
|
–
|
–
|
–
|
|
|
10
|
Invus Financial Advisors
New York
|
$50.6M
|
–
|
–
|
–
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
$45.7M
|
+$12.2M
|
+425,838
|
+34%
|
|
|
12
|
Franklin Resources
San Mateo,
California
|
$24.1M
|
+$2.32M
|
+81,216
|
+10%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$21.2M
|
+$1.71M
|
+60,032
|
+8%
|
|
|
14
|
Octagon Capital Advisors
New York
|
$20.9M
|
+$10.3M
|
+360,164
|
+90%
|
|
|
15
|
TimesSquare Capital Management
New York
|
$18.9M
|
-$914K
|
-32,000
|
-4%
|
|
|
16
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$18.5M
|
-$5.28M
|
-184,950
|
-22%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$18.3M
|
+$4.78M
|
+167,335
|
+33%
|
|
|
18
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$12.7M
|
–
|
–
|
–
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$11.7M
|
+$7.23M
|
+253,089
|
+147%
|
|
|
20
|
|
$11.4M
|
-$4.7M
|
-164,720
|
-28%
|
|
|
21
|
Two Sigma Advisers
New York
|
$10.3M
|
-$2.57M
|
-89,900
|
-19%
|
|
|
22
|
|
$9.75M
|
-$5.84M
|
-204,363
|
-37%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$9.46M
|
+$322K
|
+11,288
|
+3%
|
|
|
24
|
BNP Paribas Asset Management
Paris,
France
|
$8.56M
|
+$8.91M
|
+311,796
|
New
|
|
|
25
|
Ameriprise
Minneapolis,
Minnesota
|
$8.2M
|
-$30.6M
|
-1,071,985
|
-78%
|
|
