|
1
|
|
$234M
|
+$21.3M
|
+805,534
|
+10%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$117M
|
+$4.6M
|
+173,854
|
+4%
|
|
|
3
|
State Street
Boston,
Massachusetts
|
$108M
|
-$7.77M
|
-293,789
|
-7%
|
|
|
4
|
PFM Health Sciences
San Francisco,
California
|
$88.5M
|
+$973K
|
+36,775
|
+1%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$87.8M
|
+$902K
|
+34,092
|
+1%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$71.1M
|
-$32.9M
|
-1,243,928
|
-31%
|
|
|
7
|
Octagon Capital Advisors
New York
|
$69.8M
|
-$43.8K
|
-1,658
|
-0.1%
|
|
|
8
|
Invus Financial Advisors
New York
|
$42.2M
|
–
|
–
|
–
|
|
|
9
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$39M
|
-$11.2M
|
-423,108
|
-22%
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$37.5M
|
–
|
–
|
–
|
|
|
11
|
AllianceBernstein
Nashville,
Tennessee
|
$27.1M
|
-$2.43M
|
-91,901
|
-8%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$23.8M
|
+$1.74M
|
+65,963
|
+8%
|
|
|
13
|
Decheng Capital Management III (Cayman)
Grand Cayman,
Cayman Islands
|
$22.8M
|
–
|
–
|
–
|
|
|
14
|
|
$22.6M
|
-$2.93M
|
-110,747
|
-11%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$18.1M
|
+$303K
|
+11,458
|
+2%
|
|
|
16
|
Dimensional Fund Advisors
Austin,
Texas
|
$17.8M
|
+$9.5M
|
+359,339
|
+112%
|
|
|
17
|
Perceptive Advisors
New York
|
$17.4M
|
+$17.6M
|
+666,477
|
New
|
|
|
18
|
Finepoint Capital
Boston,
Massachusetts
|
$16.9M
|
+$2.95M
|
+111,586
|
+21%
|
|
|
19
|
BNP Paribas Asset Management
Paris,
France
|
$16.3M
|
+$1.69M
|
+63,962
|
+11%
|
|
|
20
|
|
$13.2M
|
-$356K
|
-13,459
|
-3%
|
|
|
21
|
Bank of New York Mellon
New York
|
$12.3M
|
+$1.25M
|
+47,247
|
+11%
|
|
|
22
|
|
$11.7M
|
-$101K
|
-3,821
|
-0.8%
|
|
|
23
|
Sofinnova Investments
Menlo Park,
California
|
$9.98M
|
+$10.1M
|
+381,345
|
New
|
|
|
24
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$9.94M
|
-$582
|
-22
|
-0%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$9.92M
|
+$947K
|
+35,813
|
+10%
|
|
