|
1
|
|
$131M
|
+$322K
|
+9,597
|
+0.2%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$125M
|
+$18.9M
|
+562,881
|
+17%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$111M
|
+$2.87M
|
+85,778
|
+3%
|
|
|
4
|
PFM Health Sciences
San Francisco,
California
|
$108M
|
–
|
–
|
–
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$105M
|
+$4.26M
|
+127,118
|
+4%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$103M
|
-$75.7M
|
-2,258,257
|
-41%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$86.8M
|
+$18.7M
|
+557,988
|
+25%
|
|
|
8
|
Alphabet Inc
Mountain View,
California
|
$80.9M
|
–
|
–
|
–
|
|
|
9
|
Octagon Capital Advisors
New York
|
$78.6M
|
+$13.2M
|
+394,743
|
+19%
|
|
|
10
|
Invus Financial Advisors
New York
|
$50.9M
|
–
|
–
|
–
|
|
|
11
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$49.1M
|
-$3.15M
|
-93,978
|
-6%
|
|
|
12
|
Boxer Capital
San Diego,
California
|
$45.2M
|
–
|
–
|
–
|
|
|
13
|
AllianceBernstein
Nashville,
Tennessee
|
$33.8M
|
+$34.4M
|
+1,025,643
|
+2,315%
|
|
|
14
|
Avidity Partners Management
Dallas,
Texas
|
$28.8M
|
+$30.6M
|
+912,000
|
New
|
|
|
15
|
Decheng Capital Management III (Cayman)
Grand Cayman,
Cayman Islands
|
$27.5M
|
+$29.1M
|
+869,790
|
New
|
|
|
16
|
TimesSquare Capital Management
New York
|
$25.9M
|
-$4.78M
|
-142,770
|
-15%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$25.2M
|
+$939K
|
+28,030
|
+4%
|
|
|
18
|
BNP Paribas Asset Management
Paris,
France
|
$25.2M
|
-$2.15M
|
-64,203
|
-7%
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$23.9M
|
-$14.3M
|
-427,766
|
-36%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$18.9M
|
-$800K
|
-23,862
|
-4%
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$13.8M
|
+$6.38M
|
+190,527
|
+77%
|
|
|
22
|
|
$13.8M
|
+$5.61M
|
+167,381
|
+62%
|
|
|
23
|
Perceptive Advisors
New York
|
$12.8M
|
+$13.6M
|
+405,000
|
New
|
|
|
24
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$12M
|
–
|
–
|
–
|
|
|
25
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$10.7M
|
+$1.85M
|
+55,270
|
+20%
|
|
