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Protagonist Therapeutics

272 hedge funds and large institutions have $4.7B invested in Protagonist Therapeutics in 2025 Q3 according to their latest regulatory filings, with 44 funds opening new positions, 83 increasing their positions, 109 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

0.9% less ownership

Funds ownership: 114.51%113.62% (-0.9%)

24% less repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 109

29% less funds holding in top 10

Funds holding in top 10: 1410 (-4)

Holders
272
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$12.2M
Puts
$3.45M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
CGH
201
Crossmark Global Holdings
Texas
$263K
Bank of Montreal
202
Bank of Montreal
Ontario, Canada
$257K
TRCT
203
Tower Research Capital (TRC)
New York
$253K
VCIM
204
Velan Capital Investment Management
Georgia
$246K
FC
205
FORA Capital
Florida
$245K
Wealth Enhancement Advisory Services
206
Wealth Enhancement Advisory Services
Minnesota
$230K
VCA
207
Verdence Capital Advisors
Maryland
$229K
CAPTRUST Financial Advisors
208
CAPTRUST Financial Advisors
North Carolina
$220K
QT
209
Quantbot Technologies
New York
$219K
VPIM
210
Vanguard Personalized Indexing Management
California
$219K
IFU
211
iSAM Funds (UK)
United Kingdom
$207K
FRM
212
Fox Run Management
Connecticut
$206K
Rockefeller Capital Management
213
Rockefeller Capital Management
New York
$198K
NS
214
NBC Securities
Alabama
$196K
PNC Financial Services Group
215
PNC Financial Services Group
Pennsylvania
$182K
Mirae Asset Global Investments
216
Mirae Asset Global Investments
South Korea
$160K
VIA
217
Virtus Investment Advisers
Connecticut
$134K
GI
218
GAMMA Investing
California
$109K
A
219
AlphaQuest
New York
$107K
SAM
220
Smartleaf Asset Management
Massachusetts
$91.4K
Osaic Holdings
221
Osaic Holdings
Arizona
$91K
QCG
222
Quadrant Capital Group
Ohio
$89.8K
GFM
223
GF Fund Management
China
$88.9K
C
224
Covestor
United Kingdom
$66K
WC
225
Wexford Capital
Florida
$62.5K