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Protagonist Therapeutics
PTGX

Overview Fund Activity

271 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 50 funds opening new positions, 119 increasing their positions, 77 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
271
Holders Change
-3
Holders Change %
-1.09%
% of All Funds
3.63%
Holding in Top 10
14
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.19%
New
50
Increased
119
Reduced
77
Closed
49
Calls
$18.4M
Puts
$20.8M
Net Calls
-$2.39M
Net Calls Change
-$21.6M

Top Buyers

1
UBS Group
UBS Group
Switzerland
$138M
2
CC
Commodore Capital
New York
$59.4M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$60.4M
4
BI
BVF Inc
California
$177M
5
Holocene Advisors
Holocene Advisors
New York
$29.3M

Top Sellers

1
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$51.8M
2
Focus Partners Wealth
Focus Partners Wealth
Massachusetts
$0
3
NVCHI
New Vernon Capital Holdings II
New Jersey
$398K
4
AGP
Artia Global Partners
Florida
$1.27M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$3.81M
Name Holding Trade Value Shares
Change 		Shares
Change %
COPPSERS
151
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$880K +$91.3K +1,651 +12%
DekaBank Deutsche Girozentrale
152
DekaBank Deutsche Girozentrale
Germany
$879K – – –
MWM
153
Moran Wealth Management
Florida
$871K -$7.41K -134 -0.8%
Mariner
154
Mariner
Kansas
$868K -$51.4K -930 -6%
ProShare Advisors
155
ProShare Advisors
Maryland
$850K -$76.4K -1,382 -8%
Millennium Management
156
Millennium Management
New York
$840K -$6.58M -119,078 -89%
UOC
157
UBS O'Connor
Illinois
$803K +$65.4K +1,183 +9%
PWS
158
Precision Wealth Strategies
Missouri
$793K +$793K +14,339 New
ASRS
159
Arizona State Retirement System
Arizona
$792K +$84.3K +1,525 +12%
OPERF
160
Oregon Public Employees Retirement Fund
Oregon
$785K +$27.6K +500 +4%
EAM
161
Erste Asset Management
Austria
$752K – – –
PFSRSONJ
162
Police & Firemen's Retirement System of New Jersey
New Jersey
$744K +$29.2K +528 +4%
Natixis Advisors
163
Natixis Advisors
Massachusetts
$743K +$743K +13,442 New
Teacher Retirement System of Texas
164
Teacher Retirement System of Texas
Texas
$730K +$65.2K +1,180 +10%
AG
165
Algert Global
California
$722K -$310K -5,610 -30%
HIS
166
Harvest Investment Services
Illinois
$720K -$159K -2,882 -18%
RA
167
Royce & Associates
New York
$677K – – –
FSA
168
Franklin Street Advisors
North Carolina
$625K – – –
KK
169
KLP Kapitalforvaltning
Norway
$575K +$94K +1,700 +20%
BAM
170
Bosun Asset Management
Illinois
$565K +$565K +10,226 New
CA
171
Cache Advisors
California
$561K – – –
Zurich Cantonal Bank
172
Zurich Cantonal Bank
Switzerland
$557K +$54.2K +981 +11%
HighTower Advisors
173
HighTower Advisors
Illinois
$552K +$191K +3,462 +53%
Cerity Partners
174
Cerity Partners
New York
$537K +$26.4K +477 +5%
Bank of Montreal
175
Bank of Montreal
Ontario, Canada
$533K +$35.8K +642 +7%
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7
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