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Protagonist Therapeutics

272 hedge funds and large institutions have $4.7B invested in Protagonist Therapeutics in 2025 Q3 according to their latest regulatory filings, with 44 funds opening new positions, 83 increasing their positions, 109 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

0.9% less ownership

Funds ownership: 114.51%113.62% (-0.9%)

24% less repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 109

29% less funds holding in top 10

Funds holding in top 10: 1410 (-4)

Holders
272
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$12.2M
Puts
$3.45M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
OPERF
151
Oregon Public Employees Retirement Fund
Oregon
$877K
ProShare Advisors
152
ProShare Advisors
Maryland
$876K
BNP Paribas Financial Markets
153
BNP Paribas Financial Markets
France
$873K
Teacher Retirement System of Texas
154
Teacher Retirement System of Texas
Texas
$804K
PAP
155
Persistent Asset Partners
Hong Kong
$783K
FSA
156
Franklin Street Advisors
North Carolina
$751K
Ensign Peak Advisors
157
Ensign Peak Advisors
Utah
$730K
CIM
158
Cambria Investment Management
California
$727K
KK
159
KLP Kapitalforvaltning
Norway
$691K
CA
160
Cache Advisors
California
$674K
Zurich Cantonal Bank
161
Zurich Cantonal Bank
Switzerland
$669K
HF
162
HRT Financial
New York
$629K
TI
163
Tidal Investments
Wisconsin
$594K
RAM
164
Resona Asset Management
Japan
$580K
Cerity Partners
165
Cerity Partners
New York
$572K
HighTower Advisors
166
HighTower Advisors
Illinois
$572K
AQR Capital Management
167
AQR Capital Management
Connecticut
$569K
MSRPS
168
Maryland State Retirement & Pension System
Maryland
$558K
Aviva
169
Aviva
United Kingdom
$518K
Capstone Investment Advisors
170
Capstone Investment Advisors
New York
$510K
BHCM
171
Brevan Howard Capital Management
Jersey
$505K
XT
172
XTX Topco
Cayman Islands
$482K
NVCHI
173
New Vernon Capital Holdings II
New Jersey
$478K
II
174
Inspire Investing
Idaho
$461K
BCI
175
Brinker Capital Investments
Pennsylvania
$460K