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Protagonist Therapeutics

272 hedge funds and large institutions have $4.7B invested in Protagonist Therapeutics in 2025 Q3 according to their latest regulatory filings, with 44 funds opening new positions, 83 increasing their positions, 109 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

0.9% less ownership

Funds ownership: 114.51%113.62% (-0.9%)

24% less repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 109

29% less funds holding in top 10

Funds holding in top 10: 1410 (-4)

Holders
272
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$12.2M
Puts
$3.45M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
GC
126
Guggenheim Capital
Illinois
$1.23M
WG
127
Winton Group
United Kingdom
$1.23M
YCM
128
Yousif Capital Management
Michigan
$1.22M
PA
129
Profund Advisors
Maryland
$1.21M
JGC
130
J. Goldman & Co
New York
$1.2M
GIM
131
Glenmede Investment Management
Pennsylvania
$1.2M
SO
132
STRS Ohio
Ohio
$1.18M
TRSOTSOK
133
Teachers Retirement System of the State of Kentucky
Kentucky
$1.15M
RA
134
Royce & Associates
New York
$1.13M
Natixis Advisors
135
Natixis Advisors
Massachusetts
$1.12M
AB
136
Amalgamated Bank
New York
$1.12M
Comerica Bank
137
Comerica Bank
Texas
$1.09M
State Board of Administration of Florida Retirement System
138
State Board of Administration of Florida Retirement System
Florida
$1.08M
MWM
139
Moran Wealth Management
Florida
$1.08M
PFSRSONJ
140
Police & Firemen's Retirement System of New Jersey
New Jersey
$1.07M
CUAMC
141
China Universal Asset Management Company
China
$1.06M
VRS
142
Virginia Retirement Systems
Virginia
$1.04M
DekaBank Deutsche Girozentrale
143
DekaBank Deutsche Girozentrale
Germany
$1.03M
COPPSERS
144
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$989K
JG
145
Jain Global
New York
$986K
ASRS
146
Arizona State Retirement System
Arizona
$974K
WAM
147
Weiss Asset Management
Massachusetts
$951K
Mariner
148
Mariner
Kansas
$900K
Pathstone Holdings
149
Pathstone Holdings
New Jersey
$888K
EAM
150
Erste Asset Management
Austria
$879K