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Protagonist Therapeutics
PTGX

Overview Fund Activity

270 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 50 funds opening new positions, 119 increasing their positions, 76 reducing their positions, and 49 closing their positions.

Holders
270
Holders Change
-4
Holders Change %
-1.46%
% of All Funds
3.63%
Holding in Top 10
14
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.19%
New
50
Increased
119
Reduced
76
Closed
49
Calls
$11.6M
Puts
$15.9M
Net Calls
-$4.31M
Net Calls Change
-$23.5M

Top Buyers

1
UBS Group
1
UBS Group
Switzerland
$138M
2
CC
2
Commodore Capital
New York
$59.4M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$60.4M
4
BI
4
BVF Inc
California
$177M
5
Holocene Advisors
5
Holocene Advisors
New York
$29.3M

Top Sellers

1
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$51.8M
2
Focus Partners Wealth
2
Focus Partners Wealth
Massachusetts
$0
3
NVCHI
3
New Vernon Capital Holdings II
New Jersey
$398K
4
AGP
4
Artia Global Partners
Florida
$1.27M
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$3.81M
Name Market Value Shares Shares
Change 		Shares
Change %
State of New Jersey Common Pension Fund D
101
State of New Jersey Common Pension Fund D
New Jersey
$2.27M 41,025 -12,711 -24%
Universal-Beteiligungs- und Servicegesellschaft
102
Universal-Beteiligungs- und Servicegesellschaft
Germany
$2.24M 40,484 +36,288 +865%
AA
103
ALPS Advisors
Colorado
$2.22M 40,220 -12,754 -24%
GAM
104
Gotham Asset Management
New York
$2.06M 37,287 +14,215 +62%
SOADOR
105
State of Alaska Department of Revenue
Alaska
$2.04M 36,906 +3,883 +12%
TI
106
Trexquant Investment
Connecticut
$1.99M 36,018 -67,965 -65%
Mirae Asset Global ETFs Holdings
107
Mirae Asset Global ETFs Holdings
Hong Kong
$1.98M 35,841 -1,562 -4%
JGC
108
J. Goldman & Co
New York
$1.98M 35,828 -29,416 -45%
MIM
109
MetLife Investment Management
New Jersey
$1.92M 34,770 -20 -0.1%
Man Group
110
Man Group
United Kingdom
$1.88M 34,013 -94,593 -74%
IIM
111
INTECH Investment Management
Florida
$1.88M 33,953 +2,971 +10%
State of Wisconsin Investment Board
112
State of Wisconsin Investment Board
Wisconsin
$1.82M 32,988 -20,752 -39%
Massachusetts Financial Services
113
Massachusetts Financial Services
Massachusetts
$1.78M 32,123 +397 +1%
HSA
114
Hussman Strategic Advisors
Maryland
$1.74M 31,500 -21,000 -40%
Creative Planning
115
Creative Planning
Kansas
$1.67M 30,204 +12,871 +74%
LSERS
116
Louisiana State Employees Retirement System
Louisiana
$1.6M 29,000 +900 +3%
IMRF
117
Illinois Municipal Retirement Fund
Illinois
$1.52M 27,569 +8,060 +41%
Citadel Advisors
118
Citadel Advisors
Florida
$1.5M 27,201 -126,866 -82%
BHCM
119
Brevan Howard Capital Management
Jersey
$1.49M 26,994 +10,880 +68%
State of Tennessee, Department of Treasury
120
State of Tennessee, Department of Treasury
Tennessee
$1.44M 25,990 -495 -2%
Envestnet Asset Management
121
Envestnet Asset Management
Illinois
$1.32M 23,878 +7,199 +43%
TI
122
Tidal Investments
Wisconsin
$1.31M 23,777 +4,367 +22%
YCM
123
Yousif Capital Management
Michigan
$1.29M 23,404 +1,067 +5%
Ensign Peak Advisors
124
Ensign Peak Advisors
Utah
$1.28M 23,136 -3,900 -14%
AGP
125
Artia Global Partners
Florida
$1.27M 22,951 -310,900 -93%
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5
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