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Praxis Precision Medicines
PRAX

Name Holding Trade Value Shares
Change 		Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$85M +$29.4M +654,362 +89%
CAM
2
Cormorant Asset Management
Massachusetts
$79.9M +$30.4M +676,655 +107%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$58.2M +$11.7M +261,888 +38%
RCM
4
RA Capital Management
Massachusetts
$50.5M +$37.2M +828,380 New
PA
5
Perceptive Advisors
New York
$50.1M +$36.9M +821,589 New
Vanguard Group
6
Vanguard Group
Pennsylvania
$45.4M +$16.7M +373,131 +101%
VA
7
VR Adviser
New York
$43.1M +$15.8M +352,500 +100%
Verition Fund Management
8
Verition Fund Management
Connecticut
$33.3M -$7.07M -157,592 -22%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$32.7M +$24M +535,999 New
PHS
10
PFM Health Sciences
California
$29.1M -$8.03M -178,943 -27%
O
11
OrbiMed
New York
$28.1M +$20.7M +460,512 New
Fidelity Investments
12
Fidelity Investments
Massachusetts
$27M +$19.9M +442,506 +384,788%
VCIM
13
Velan Capital Investment Management
Georgia
$21.4M +$224K +5,000 +1%
KCM
14
Kingdon Capital Management
New York
$21.4M +$150K +3,335 +1%
5VM
15
5AM Venture Management
California
$20.7M +$15.3M +340,000 New
Janus Henderson Group
16
Janus Henderson Group
$18.9M +$13.9M +310,059 New
DCM
17
Driehaus Capital Management
Illinois
$16.3M +$12M +266,496 New
OCA
18
Octagon Capital Advisors
New York
$15.9M +$11.7M +260,000 New
LCM
19
Laurion Capital Management
New York
$13.7M +$10.1M +225,000 New
BlackRock
20
BlackRock
New York
$13.5M +$4.27M +95,209 +75%
VPC
21
Vestal Point Capital
New York
$12.8M +$9.42M +210,000 New
CIBC Asset Management
22
CIBC Asset Management
Ontario, Canada
$11.7M +$827K +18,436 +11%
SCM
23
Silverarc Capital Management
Massachusetts
$11.6M -$4.18M -93,285 -33%
SFM
24
Sphera Funds Management
Israel
$10.8M -$6.81M -151,847 -46%
Millennium Management
25
Millennium Management
New York
$10.8M +$6.94M +154,606 +692%
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