|
1
|
Janus Henderson Group
London,
|
$955M
|
+$88.7M
|
+476,227
|
+17%
|
|
|
2
|
|
$613M
|
+$51.7M
|
+277,420
|
+15%
|
|
|
3
|
Perceptive Advisors
New York
|
$588M
|
+$80.3M
|
+431,432
|
+28%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$431M
|
+$36.1M
|
+193,647
|
+15%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$400M
|
+$245M
|
+1,315,464
|
+3,044%
|
|
|
6
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$370M
|
+$234M
|
+1,255,162
|
New
|
|
|
7
|
Baker Bros. Advisors
New York
|
$332M
|
+$81.4M
|
+437,000
|
+63%
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$285M
|
-$262M
|
-1,408,772
|
-59%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$280M
|
-$9.31M
|
-50,000
|
-5%
|
|
|
10
|
Driehaus Capital Management
Chicago,
Illinois
|
$275M
|
+$80.5M
|
+432,510
|
+86%
|
|
|
11
|
Deerfield Management
New York
|
$266M
|
+$11.6M
|
+62,500
|
+7%
|
|
|
12
|
|
$262M
|
+$45.9M
|
+246,394
|
+38%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$260M
|
-$4.64M
|
-24,893
|
-3%
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$232M
|
-$40.5M
|
-217,503
|
-22%
|
|
|
15
|
|
$211M
|
+$22.9M
|
+123,163
|
+21%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$166M
|
+$19.6M
|
+105,347
|
+23%
|
|
|
17
|
Barclays
London,
United Kingdom
|
$156M
|
+$84.6M
|
+454,114
|
+593%
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$154M
|
+$7.43M
|
+39,902
|
+8%
|
|
|
19
|
Point72 Asset Management
Stamford,
Connecticut
|
$145M
|
-$187M
|
-1,003,640
|
-67%
|
|
|
20
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$120M
|
-$185K
|
-992
|
-0.2%
|
|
|
21
|
Logos Global Management
San Francisco,
California
|
$111M
|
+$46.6M
|
+250,000
|
+200%
|
|
|
22
|
RA Capital Management
Boston,
Massachusetts
|
$110M
|
+$69.6M
|
+373,787
|
New
|
|
|
23
|
Soleus Capital Management
Greenwich,
Connecticut
|
$107M
|
-$92.4M
|
-496,200
|
-58%
|
|
|
24
|
Franklin Resources
San Mateo,
California
|
$105M
|
+$7.81M
|
+41,917
|
+13%
|
|
|
25
|
Vivo Capital
Palo Alto,
California
|
$96.9M
|
+$24.2M
|
+130,000
|
+65%
|
|
