|
1
|
Janus Henderson Group
London,
|
$1.11B
|
+$67.7M
|
+218,777
|
+7%
|
|
|
2
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$797M
|
+$377M
|
+1,217,318
|
+97%
|
|
|
3
|
|
$749M
|
+$76.2M
|
+246,429
|
+12%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$696M
|
+$248M
|
+802,268
|
+59%
|
|
|
5
|
Perceptive Advisors
New York
|
$656M
|
+$12.4M
|
+40,000
|
+2%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$565M
|
+$194M
|
+626,710
|
+56%
|
|
|
7
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$394M
|
+$378M
|
+1,221,944
|
New
|
|
|
8
|
Deerfield Management
New York
|
$310M
|
+$18.6M
|
+60,000
|
+7%
|
|
|
9
|
Driehaus Capital Management
Chicago,
Illinois
|
$306M
|
+$5M
|
+16,164
|
+2%
|
|
|
10
|
Cormorant Asset Management
Boston,
Massachusetts
|
$285M
|
-$20M
|
-64,500
|
-7%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$285M
|
+$626K
|
+2,023
|
+0.2%
|
|
|
12
|
|
$269M
|
-$17.4M
|
-56,398
|
-6%
|
|
|
13
|
Adage Capital Partners
Boston,
Massachusetts
|
$263M
|
-$46.3M
|
-149,574
|
-15%
|
|
|
14
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$244M
|
+$234M
|
+756,748
|
New
|
|
|
15
|
|
$229M
|
-$1.69M
|
-5,450
|
-0.8%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$210M
|
+$27.4M
|
+88,525
|
+16%
|
|
|
17
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$203M
|
-$48M
|
-155,135
|
-20%
|
|
|
18
|
Bank of America
Charlotte,
North Carolina
|
$172M
|
+$3.66M
|
+11,841
|
+2%
|
|
|
19
|
RA Capital Management
Boston,
Massachusetts
|
$120M
|
–
|
–
|
–
|
|
|
20
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$116M
|
+$21.4M
|
+69,151
|
+24%
|
|
|
21
|
Vivo Capital
Palo Alto,
California
|
$109M
|
+$3.09M
|
+10,000
|
+3%
|
|
|
22
|
Soleus Capital Management
Greenwich,
Connecticut
|
$106M
|
-$10M
|
-32,449
|
-9%
|
|
|
23
|
Logos Global Management
San Francisco,
California
|
$91.8M
|
-$27.8M
|
-90,000
|
-24%
|
|
|
24
|
Pictet Asset Management
Carouge,
Switzerland
|
$91.4M
|
+$14.2M
|
+46,056
|
+19%
|
|
|
25
|
Franklin Resources
San Mateo,
California
|
$89M
|
-$24.7M
|
-79,951
|
-22%
|
|
