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Praxis Precision Medicines

250 hedge funds and large institutions have $8.69B invested in Praxis Precision Medicines in 2025 Q4 according to their latest regulatory filings, with 115 funds opening new positions, 87 increasing their positions, 44 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

700% more funds holding in top 10

Funds holding in top 10: 324 (+21)

667% more first-time investments, than exits

New positions opened: 115 | Existing positions closed: 15

564% more capital invested

Capital invested by funds: $1.31B → $8.69B (+$7.38B)

98% more repeat investments, than reductions

Existing positions increased: 87 | Existing positions reduced: 44

64% more funds holding

Funds holding: 152250 (+98)

0.66% more ownership

Funds ownership: 117.18%117.84% (+0.66%)

8% less call options, than puts

Call options by funds: $219M | Put options by funds: $238M

Holders
250
Holders Change
+98
Holders Change %
+64.47%
% of All Funds
3.04%
Holding in Top 10
24
Holding in Top 10 Change
+21
Holding in Top 10 Change %
+700%
% of All Funds
0.29%
New
115
Increased
87
Reduced
44
Closed
15
Calls
$219M
Puts
$238M
Net Calls
-$18.3M
Net Calls Change
-$22.9M
Name Holding Trade Value Shares
Change
Change in
Stake
CM
76
Caption Management
Oklahoma
$9.81M +$5.02M +26,943 +424%
BGI
77
B Group Inc
Texas
$9.8M +$323K +1,737 +6%
CAM
78
Congress Asset Management
Massachusetts
$9.21M +$150K +807 +3%
PHS
79
PFM Health Sciences
California
$9.18M -$5.48M -29,415 -49%
Lord, Abbett & Co
80
Lord, Abbett & Co
New Jersey
$9.06M +$5.73M +30,756 New
ACH
81
ArrowMark Colorado Holdings
Colorado
$8.84M +$5.59M +30,000 New
AQR Capital Management
82
AQR Capital Management
Connecticut
$8.5M +$1.29M +6,924 +32%
RhumbLine Advisers
83
RhumbLine Advisers
Massachusetts
$8.35M +$285K +1,530 +6%
HS
84
HighVista Strategies
Massachusetts
$7.62M -$12.9M -69,161 -73%
Neuberger Berman Group
85
Neuberger Berman Group
New York
$7.57M +$4.78M +25,678 New
Mirae Asset Global ETFs Holdings
86
Mirae Asset Global ETFs Holdings
Hong Kong
$7.54M +$507K +2,723 +12%
Wells Fargo
87
Wells Fargo
California
$7.44M +$2.17M +11,630 +85%
AllianceBernstein
88
AllianceBernstein
Tennessee
$7.39M +$1.31M +7,010 +39%
BGM
89
Burkehill Global Management
New York
$7.37M +$4.66M +25,000 New
Dimensional Fund Advisors
90
Dimensional Fund Advisors
Texas
$6.94M -$2.58M -13,871 -37%
SPS
91
Susquehanna Portfolio Strategies
Pennsylvania
$6.85M
Two Sigma Investments
92
Two Sigma Investments
New York
$6.81M +$3.28M +17,590 +319%
TAM
93
TFG Asset Management
Cayman Islands
$6.76M +$4.27M +22,952 New
Ameriprise
94
Ameriprise
Minnesota
$6.7M +$4.23M +22,715 New
Rafferty Asset Management
95
Rafferty Asset Management
New York
$6.56M -$2.86M -15,333 -41%
Man Group
96
Man Group
United Kingdom
$6.24M +$3.94M +21,170 New
SC
97
Stempoint Capital
New York
$6.21M +$3.92M +21,067 New
BFM
98
Boothbay Fund Management
New York
$6.18M -$3.48M -18,686 -47%
EI
99
EAM Investors
California
$6.17M +$3.9M +20,941 New
Russell Investments Group
100
Russell Investments Group
United Kingdom
$6.08M +$3.02M +16,208 +368%