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Praxis Precision Medicines

250 hedge funds and large institutions have $8.69B invested in Praxis Precision Medicines in 2025 Q4 according to their latest regulatory filings, with 115 funds opening new positions, 87 increasing their positions, 44 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

700% more funds holding in top 10

Funds holding in top 10: 324 (+21)

667% more first-time investments, than exits

New positions opened: 115 | Existing positions closed: 15

564% more capital invested

Capital invested by funds: $1.31B → $8.69B (+$7.38B)

98% more repeat investments, than reductions

Existing positions increased: 87 | Existing positions reduced: 44

64% more funds holding

Funds holding: 152250 (+98)

0.66% more ownership

Funds ownership: 117.18%117.84% (+0.66%)

8% less call options, than puts

Call options by funds: $219M | Put options by funds: $238M

Holders
250
Holders Change
+98
Holders Change %
+64.47%
% of All Funds
3.04%
Holding in Top 10
24
Holding in Top 10 Change
+21
Holding in Top 10 Change %
+700%
% of All Funds
0.29%
New
115
Increased
87
Reduced
44
Closed
15
Calls
$219M
Puts
$238M
Net Calls
-$18.3M
Net Calls Change
-$22.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Marshall Wace
51
Marshall Wace
United Kingdom
$20.4M +$205K +1,101 +2%
EAM
52
Eventide Asset Management
Massachusetts
$19.8M +$12.5M +67,100 New
Renaissance Technologies
53
Renaissance Technologies
New York
$19.5M +$12.3M +66,230 New
7IH
54
72 Investment Holdings
Connecticut
$19.4M
Ensign Peak Advisors
55
Ensign Peak Advisors
Utah
$18.9M +$12M +64,283 New
EAM
56
Exome Asset Management
New York
$17.1M -$8.17M -43,874 -43%
JP Morgan Chase
57
JP Morgan Chase
New York
$16.3M +$5.42M +29,092 +111%
Deutsche Bank
58
Deutsche Bank
Germany
$15M +$6.88M +36,955 +267%
N
59
Nuveen
North Carolina
$14.7M +$2.13M +11,421 +30%
BCM
60
Boxer Capital Management
California
$13.7M +$8.65M +46,457 New
TD Asset Management
61
TD Asset Management
Ontario, Canada
$13.6M +$980K +5,262 +13%
KCA
62
KVP Capital Advisors
California
$12.6M +$7.99M +42,900 New
MAP
63
Moody Aldrich Partners
Massachusetts
$12.3M +$7.77M +41,731 New
SC
64
SummitTX Capital
Texas
$12.3M +$1.25M +6,701 +19%
Swiss National Bank
65
Swiss National Bank
Switzerland
$11.9M +$931K +5,000 +14%
IHAM
66
Integral Health Asset Management
New York
$11.8M +$7.45M +40,000 New
II
67
Ishara Investments
California
$11.8M +$7.45M +40,000 New
D.E. Shaw & Co
68
D.E. Shaw & Co
New York
$11M +$3.29M +17,685 +89%
Universal-Beteiligungs- und Servicegesellschaft
69
Universal-Beteiligungs- und Servicegesellschaft
Germany
$11M +$6.96M +37,377 New
EF
70
Empowered Funds
Pennsylvania
$10.9M +$6.86M +36,852 New
RAM
71
Readystate Asset Management
Illinois
$10.8M -$13.5M -72,385 -66%
FTM
72
First Turn Management
California
$10.5M +$6.66M +35,749 New
UBS AM
73
UBS AM
Illinois
$10.4M +$2.15M +11,532 +49%
Citadel Advisors
74
Citadel Advisors
Florida
$10.3M +$5.05M +27,119 +348%
Manulife (Manufacturers Life Insurance)
75
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$9.86M -$473K -2,538 -7%