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Praxis Precision Medicines
PRAX

68 hedge funds and large institutions have $1.19B invested in Praxis Precision Medicines in 2021 Q1 according to their latest regulatory filings, with 11 funds opening new positions, 25 increasing their positions, 14 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

79% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 14

0.02% more ownership

Funds ownership: 6.31% → 6.33% (+0.02%)

8% less first-time investments, than exits

New positions opened: 11 | Existing positions closed: 12

1% less funds holding

Funds holding: 69 → 68 (-1)

40% less capital invested

Capital invested by funds: $1.96B → $1.19B (-$776M)

67% less funds holding in top 10

Funds holding in top 10: 6 → 2 (-4)

Holders
68
Holders Change
-1
Holders Change %
-1.45%
% of All Funds
1.19%
Holding in Top 10
2
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-66.67%
% of All Funds
0.04%
New
11
Increased
25
Reduced
14
Closed
12
Calls
$3K
Puts
–
Net Calls
+$3K
Net Calls Change
+$3K

Top Buyers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
+$32.4M
2
State Street
State Street
Massachusetts
+$26.5M
3
AllianceBernstein
AllianceBernstein
Tennessee
+$9.26M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$7.87M
5
ACP
Acuta Capital Partners
California
+$3.73M

Top Sellers

Rank Fund Capital Flow
1
DM
Deerfield Management
New York
-$19.3M
2
O
OrbiMed
New York
-$14.1M
3
FCM
Farallon Capital Management
California
-$13.8M
4
UBS Group
UBS Group
Switzerland
-$6.4M
5
SFM
Sphera Funds Management
Israel
-$5.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$3.95M -$314K -442 -5%
Goldman Sachs
27
Goldman Sachs
New York
$3.27M +$1.61M +2,263 +52%
TCM
28
Tekla Capital Management
Massachusetts
$2.46M – – –
Charles Schwab
29
Charles Schwab
California
$2.38M +$137K +192 +4%
N
30
Nuveen
North Carolina
$1.85M +$756K +1,063 +39%
LCM
31
Laurion Capital Management
New York
$1.64M – – –
Citigroup
32
Citigroup
New York
$1.53M +$2.11M +2,966 +2,032%
MS
33
Maven Securities
Jersey
$1.52M +$1.43M +2,011 +163%
Rafferty Asset Management
34
Rafferty Asset Management
New York
$1.23M +$1.78M +2,506 New
Bank of New York Mellon
35
Bank of New York Mellon
New York
$1.09M +$170K +239 +12%
Millennium Management
36
Millennium Management
New York
$842K +$1.22M +1,713 New
California Public Employees Retirement System
37
California Public Employees Retirement System
California
$692K -$93.9K -132 -9%
Los Angeles Capital Management
38
Los Angeles Capital Management
California
$604K +$874K +1,229 New
California State Teachers Retirement System (CalSTRS)
39
California State Teachers Retirement System (CalSTRS)
California
$545K -$2.13K -3 -0.3%
Bank of America
40
Bank of America
North Carolina
$409K +$470K +661 +389%
RhumbLine Advisers
41
RhumbLine Advisers
Massachusetts
$347K +$24.2K +34 +5%
New York State Common Retirement Fund
42
New York State Common Retirement Fund
New York
$344K +$90.3K +127 +22%
CF
43
CNA Financial
Illinois
$325K +$91.7K +129 +24%
Deutsche Bank
44
Deutsche Bank
Germany
$246K -$32K -45 -8%
JP Morgan Chase
45
JP Morgan Chase
New York
$244K +$88.9K +125 +34%
BFS
46
Bradley Foster & Sargent
Connecticut
$229K – – –
FMBTD
47
First Midwest Bank Trust Division
Illinois
$227K +$328K +462 New
Manulife (Manufacturers Life Insurance)
48
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$208K – – –
MIM
49
MetLife Investment Management
New Jersey
$170K – – –
Morgan Stanley
50
Morgan Stanley
New York
$144K -$470K -661 -69%
1
2
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PRAX Hedge Fund Activity: Q1 2021 in Review

68 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q1 2021, worth a combined $1.19B — down 40% from $1.96B a quarter earlier.

Sellers outnumbered buyers: 12 funds closed out of PRAX and 11 opened new positions — a net loss of 1 holder — while 14 trimmed existing stakes and 25 added.

The largest buyer was Fidelity Investments, adding an estimated $32.4M. The largest seller was Deerfield Management, exiting entirely with an estimated $19.3M sold.

  • 68 institutional investors held Praxis Precision Medicines (PRAX) as of Q1 2021, down from 69 in Q4 2020.
  • Funds reported $1.19B of Praxis Precision Medicines stock for Q1 2021, down 40% quarter-over-quarter.
  • 11 funds opened new Praxis Precision Medicines positions in Q1 2021 and 12 closed out, a net change of -1 holder.
  • The largest Praxis Precision Medicines buyer in Q1 2021 was Fidelity Investments, an estimated $32.4M added.
  • The largest Praxis Precision Medicines seller in Q1 2021 was Deerfield Management, an estimated $19.3M sold.

Based on aggregated 13F filings for Q1 2021.