|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$299M
|
+$5.4M
|
+156,752
|
+2%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$290M
|
+$22.6M
|
+655,500
|
+11%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$286M
|
+$3.29M
|
+95,555
|
+1%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$245M
|
+$13.4M
|
+388,456
|
+7%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$240M
|
+$11.7M
|
+340,909
|
+7%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$237M
|
+$35.2M
|
+1,022,760
|
+23%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$234M
|
-$21.5M
|
-624,812
|
-10%
|
|
|
8
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$214M
|
–
|
–
|
–
|
|
|
9
|
|
$181M
|
-$4.64M
|
-134,643
|
-3%
|
|
|
10
|
Siren LLC
Greenwich,
Connecticut
|
$150M
|
+$6.47M
|
+187,837
|
+6%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$67.8M
|
-$7.1M
|
-206,276
|
-12%
|
|
|
12
|
Capital Research Global Investors
Los Angeles,
California
|
$55.1M
|
+$30.9M
|
+896,992
|
+246%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$52.1M
|
+$2.04M
|
+59,347
|
+5%
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$40.8M
|
-$8.09M
|
-234,901
|
-20%
|
|
|
15
|
Jennison Associates
New York
|
$36M
|
+$9.39M
|
+272,739
|
+49%
|
|
|
16
|
|
$35.7M
|
-$2.67M
|
-77,477
|
-9%
|
|
|
17
|
Redmile Group
San Francisco,
California
|
$35.1M
|
-$6.2M
|
-180,124
|
-18%
|
|
|
18
|
Merck & Co
Rahway,
New Jersey
|
$33.7M
|
–
|
–
|
–
|
|
|
19
|
Commodore Capital
New York
|
$32.7M
|
+$25.8M
|
+750,000
|
New
|
|
|
20
|
Deerfield Management
New York
|
$28.5M
|
+$2.07M
|
+60,000
|
+10%
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$24.6M
|
+$5.78M
|
+167,897
|
+42%
|
|
|
22
|
Eventide Asset Management
Boston,
Massachusetts
|
$24.6M
|
+$1.3M
|
+37,852
|
+7%
|
|
|
23
|
UBS Group
Zurich,
Switzerland
|
$24.3M
|
-$1.24M
|
-35,872
|
-6%
|
|
|
24
|
Citadel Advisors
Miami,
Florida
|
$22.6M
|
+$17.8M
|
+516,382
|
+20,614%
|
|
|
25
|
Woodline Partners
San Francisco,
California
|
$21.7M
|
-$934K
|
-27,134
|
-5%
|
|
