|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$276M
|
+$10.2M
|
+224,859
|
+3%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$241M
|
–
|
–
|
–
|
|
|
3
|
Wellington Management Group
Boston,
Massachusetts
|
$214M
|
+$31.1M
|
+688,967
|
+15%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$208M
|
–
|
–
|
–
|
|
|
5
|
Avoro Capital Advisors
New York
|
$207M
|
+$29.4M
|
+650,000
|
+14%
|
|
|
6
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$197M
|
–
|
–
|
–
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$197M
|
+$6.03M
|
+133,546
|
+3%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$194M
|
-$12.6M
|
-278,718
|
-5%
|
|
|
9
|
|
$175M
|
+$6.53M
|
+144,654
|
+3%
|
|
|
10
|
Siren LLC
Greenwich,
Connecticut
|
$119M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$67.9M
|
-$1.78M
|
-39,355
|
-2%
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$55.9M
|
+$2.79M
|
+61,669
|
+5%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$44.5M
|
+$2.36M
|
+52,263
|
+5%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$44.3M
|
-$13.2M
|
-292,824
|
-21%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$41.6M
|
-$689K
|
-15,249
|
-1%
|
|
|
16
|
Merck & Co
Rahway,
New Jersey
|
$31.1M
|
+$34.9M
|
+772,165
|
New
|
|
|
17
|
Jennison Associates
New York
|
$28.8M
|
-$3.65M
|
-80,748
|
-10%
|
|
|
18
|
Deerfield Management
New York
|
$23.9M
|
+$26.8M
|
+593,000
|
New
|
|
|
19
|
Woodline Partners
San Francisco,
California
|
$21.6M
|
+$557K
|
+12,334
|
+2%
|
|
|
20
|
Avidity Partners Management
Dallas,
Texas
|
$20.1M
|
–
|
–
|
–
|
|
|
21
|
UBS Group
Zurich,
Switzerland
|
$18.9M
|
+$11.4M
|
+252,223
|
+116%
|
|
|
22
|
AJU IB Investment Company
Seoul,
South Korea
|
$18.4M
|
+$20.6M
|
+457,059
|
New
|
|
|
23
|
Eventide Asset Management
Boston,
Massachusetts
|
$18.3M
|
-$2.36M
|
-52,174
|
-10%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$17.6M
|
+$2.42M
|
+53,658
|
+14%
|
|
|
25
|
|
$17.5M
|
+$9.44M
|
+209,113
|
+93%
|
|
