|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$190M
|
+$80.5M
|
+1,388,271
|
+75%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$187M
|
+$31.9M
|
+550,000
|
+21%
|
|
|
3
|
|
$179M
|
+$34.3M
|
+591,914
|
+24%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$170M
|
+$49.7M
|
+857,350
|
+42%
|
|
|
5
|
Redmile Group
San Francisco,
California
|
$164M
|
+$15.2M
|
+262,200
|
+10%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$145M
|
+$95.1M
|
+1,639,994
|
+198%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$140M
|
+$24.7M
|
+425,531
|
+22%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$138M
|
+$10.1M
|
+173,378
|
+8%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$84.6M
|
+$5.98M
|
+103,130
|
+8%
|
|
|
10
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$43.1M
|
+$6.17M
|
+106,400
|
+17%
|
|
|
11
|
AJU IB Investment Company
Seoul,
South Korea
|
$37.5M
|
–
|
–
|
–
|
|
|
12
|
Deer IX & Co
Larchmont,
New York
|
$36.2M
|
-$35.9M
|
-619,413
|
-50%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$35.2M
|
+$15M
|
+258,328
|
+76%
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$34.3M
|
+$32M
|
+551,611
|
+1,747%
|
|
|
15
|
Avidity Partners Management
Dallas,
Texas
|
$30.2M
|
+$29.8M
|
+514,500
|
New
|
|
|
16
|
Bank of New York Mellon
New York
|
$29.4M
|
+$25.1M
|
+432,300
|
+630%
|
|
|
17
|
Avoro Capital Advisors
New York
|
$26.8M
|
+$26.4M
|
+455,750
|
New
|
|
|
18
|
|
$23.5M
|
+$8.7M
|
+150,000
|
+60%
|
|
|
19
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$23.2M
|
-$928K
|
-16,000
|
-4%
|
|
|
20
|
Sphera Funds Management
Tel Aviv,
Israel
|
$21.1M
|
+$5.76M
|
+99,365
|
+38%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$19.9M
|
+$4.59M
|
+79,208
|
+31%
|
|
|
22
|
Clough Capital Partners
Boston,
Massachusetts
|
$15.9M
|
+$9.88M
|
+170,400
|
+169%
|
|
|
23
|
|
$15.6M
|
-$913K
|
-15,750
|
-6%
|
|
|
24
|
Adage Capital Partners
Boston,
Massachusetts
|
$14.7M
|
+$8.7M
|
+150,000
|
+150%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$14.3M
|
+$8.07M
|
+139,149
|
+134%
|
|
