|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$315M
|
+$11.3M
|
+254,816
|
+4%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$284M
|
+$44
|
+1
|
+0%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$244M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$242M
|
+$12.5M
|
+282,301
|
+6%
|
|
|
5
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$232M
|
-$20M
|
-453,960
|
-8%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$225M
|
-$3.03M
|
-68,650
|
-1%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$219M
|
+$13.6M
|
+308,954
|
+7%
|
|
|
8
|
Avoro Capital Advisors
New York
|
$213M
|
+$27M
|
+611,112
|
+16%
|
|
|
9
|
|
$199M
|
+$2.48M
|
+56,220
|
+1%
|
|
|
10
|
Siren LLC
Greenwich,
Connecticut
|
$141M
|
+$131M
|
+2,969,733
|
New
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$81.8M
|
-$8.06M
|
-182,547
|
-10%
|
|
|
12
|
Redmile Group
San Francisco,
California
|
$65.9M
|
-$8.21M
|
-186,019
|
-12%
|
|
|
13
|
Driehaus Capital Management
Chicago,
Illinois
|
$62.9M
|
+$48.8M
|
+1,105,290
|
+495%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$49.9M
|
-$44K
|
-996
|
-0.1%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$49.7M
|
-$5.06M
|
-114,587
|
-10%
|
|
|
16
|
Jennison Associates
New York
|
$37.8M
|
+$16.3M
|
+368,394
|
+86%
|
|
|
17
|
Deep Track Capital
Greenwich,
Connecticut
|
$28.4M
|
-$39.7M
|
-899,674
|
-60%
|
|
|
18
|
Woodline Partners
San Francisco,
California
|
$24.9M
|
+$322K
|
+7,297
|
+1%
|
|
|
19
|
Eventide Asset Management
Boston,
Massachusetts
|
$24M
|
+$2.02M
|
+45,803
|
+10%
|
|
|
20
|
Avidity Partners Management
Dallas,
Texas
|
$23.7M
|
+$22.1M
|
+500,000
|
New
|
|
|
21
|
|
$23.1M
|
-$6.34M
|
-143,661
|
-23%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$22.4M
|
+$3.1M
|
+70,241
|
+17%
|
|
|
23
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$21.5M
|
+$2.1M
|
+47,507
|
+12%
|
|
|
24
|
Boxer Capital
San Diego,
California
|
$21.3M
|
+$19.9M
|
+450,000
|
New
|
|
|
25
|
|
$20.3M
|
-$223K
|
-5,044
|
-1%
|
|
