|
1
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$183M
|
-$6.12M
|
-167,883
|
-2%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$177M
|
+$47.8M
|
+1,310,000
|
+25%
|
|
|
3
|
Wellington Management Group
Boston,
Massachusetts
|
$164M
|
+$25.1M
|
+689,547
|
+13%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$164M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$143M
|
+$12.5M
|
+344,080
|
+7%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$141M
|
–
|
–
|
–
|
|
|
7
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$134M
|
–
|
–
|
–
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$121M
|
-$15.4M
|
-421,189
|
-9%
|
|
|
9
|
|
$117M
|
-$2.68M
|
-73,400
|
-2%
|
|
|
10
|
Siren LLC
Greenwich,
Connecticut
|
$88.7M
|
+$9.86M
|
+270,580
|
+9%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$48.2M
|
+$2.62M
|
+71,918
|
+4%
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$32M
|
-$8.08M
|
-221,581
|
-16%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$31M
|
+$1.03M
|
+28,278
|
+3%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$26.9M
|
-$4.27M
|
-117,019
|
-11%
|
|
|
15
|
|
$24.5M
|
+$17.9M
|
+491,737
|
+122%
|
|
|
16
|
Janus Henderson Group
London,
|
$22.8M
|
+$14.3M
|
+393,198
|
+104%
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$21.7M
|
-$8.74M
|
-239,700
|
-23%
|
|
|
18
|
Merck & Co
Rahway,
New Jersey
|
$21.1M
|
–
|
–
|
–
|
|
|
19
|
UBS Group
Zurich,
Switzerland
|
$16.2M
|
+$4.51M
|
+123,764
|
+26%
|
|
|
20
|
Deerfield Management
New York
|
$16.2M
|
–
|
–
|
–
|
|
|
21
|
Jennison Associates
New York
|
$15.1M
|
-$6M
|
-164,647
|
-23%
|
|
|
22
|
Woodline Partners
San Francisco,
California
|
$14.4M
|
-$444K
|
-12,183
|
-2%
|
|
|
23
|
Eventide Asset Management
Boston,
Massachusetts
|
$14.4M
|
+$2.53M
|
+69,410
|
+15%
|
|
|
24
|
Millennium Management
New York
|
$14M
|
+$14.4M
|
+394,562
|
+340%
|
|
|
25
|
AJU IB Investment Company
Seoul,
South Korea
|
$12.5M
|
–
|
–
|
–
|
|
