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Disc Medicine
IRON

215 hedge funds and large institutions have $3.13B invested in Disc Medicine in 2026 Q2 according to their latest regulatory filings, with 39 funds opening new positions, 75 increasing their positions, 63 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

461% more call options, than puts

Call options by funds: $26.6M | Put options by funds: $4.75M

77% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 22

19% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 63

17% more capital invested

Capital invested by funds: $2.67B → $3.13B (+$457M)

17% more funds holding in top 10

Funds holding in top 10: 6 → 7 (+1)

6% more funds holding

Funds holding: 203 → 215 (+12)

2.06% more ownership

Funds ownership: 109.8% → 111.86% (+2.1%)

Holders
215
Holders Change
+12
Holders Change %
+5.91%
% of All Funds
2.6%
Holding in Top 10
7
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+16.67%
% of All Funds
0.08%
New
39
Increased
75
Reduced
63
Closed
22
Calls
$26.6M
Puts
$4.75M
Net Calls
+$21.9M
Net Calls Change
+$3.6M

Top Buyers

Rank Fund Capital Flow
1
VPC
Vestal Point Capital
New York
+$58.4M
2
JP Morgan Chase
JP Morgan Chase
New York
+$34.7M
3
OM
Opaleye Management
Massachusetts
+$29.8M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$22.4M
5
LGM
Logos Global Management
California
+$21.6M

Top Sellers

Rank Fund Capital Flow
1
O
OrbiMed
New York
-$48.8M
2
Fidelity Investments
Fidelity Investments
Massachusetts
-$47.6M
3
Goldman Sachs
Goldman Sachs
New York
-$37.3M
4
Jennison Associates
Jennison Associates
New York
-$11.7M
5
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$11.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
GWM
201
Geneos Wealth Management
Colorado
$951 – – –
AssetMark Inc
202
AssetMark Inc
California
$878 – – –
HNB
203
Huntington National Bank
Ohio
$878 +$825 +12 New
CFM
204
Cornerstone Financial Management
Massachusetts
$805 – – –
BFS
205
Bare Financial Services
Pennsylvania
$658 – – –
KFAS
206
Keating Financial Advisory Services
Kansas
$439 +$206 +3 +100%
EP
207
Essential Partners
California
$366 +$69 +1 +25%
GRP
208
Global Retirement Partners
California
$293 +$275 +4 New
CA
209
Clearstead Advisors
Ohio
$148 +$137 +2 New
HFS
210
Hughes Financial Services
Virginia
$146 +$69 +1 +100%
DF
211
Downshift Financial
Colorado
$146 +$137 +2 New
IA
212
IFP Advisors
Florida
$73 -$137 -2 -67%
SS
213
SBI Securities
Japan
$73 – – –
FFO
214
Fortitude Family Office
Arizona
$73 +$69 +1 New
WETS
215
Wealth Enhancement Trust Services
South Dakota
$73 +$69 +1 New
IHAM
216
Integral Health Asset Management
New York
– -$10.9M -170,000 Closed
FGP
217
Freestone Grove Partners
California
– -$4.39M -68,687 Closed
SCM
218
Sio Capital Management
New York
– -$4.17M -65,203 Closed
Renaissance Technologies
219
Renaissance Technologies
New York
– -$2.03M -31,820 Closed
NCM
220
Nantahala Capital Management
Connecticut
– -$1.64M -25,653 Closed
BFM
221
Boothbay Fund Management
New York
– -$1.47M -21,378 Closed
ZP
222
Zimmer Partners
New York
– -$1.07M -16,700 Closed
HT
223
Headlands Technologies
Illinois
– -$934K -14,611 Closed
AI
224
Atom Investors
Texas
– -$778K -12,162 Closed
GCM
225
Ghisallo Capital Management
Massachusetts
– -$639K -10,000 Closed
6 7 8
9
10

IRON Hedge Fund Activity: Q2 2026 in Review

215 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q2 2026, worth a combined $3.13B — up 17% from $2.67B a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new IRON positions and 22 closed out — a net gain of 17 holders — while 75 added to existing stakes and 63 trimmed.

The largest buyer was Vestal Point Capital, adding an estimated $58.4M. The largest seller was OrbiMed, cutting an estimated $48.8M.

  • 215 institutional investors held Disc Medicine (IRON) as of Q2 2026, up from 203 in Q1 2026.
  • Funds reported $3.13B of Disc Medicine stock for Q2 2026, up 17% quarter-over-quarter.
  • 39 funds opened new Disc Medicine positions in Q2 2026 and 22 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q2 2026 was Vestal Point Capital, an estimated $58.4M added.
  • The largest Disc Medicine seller in Q2 2026 was OrbiMed, an estimated $48.8M sold.

Based on aggregated 13F filings for Q2 2026.