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Disc Medicine

151 hedge funds and large institutions have $1.8B invested in Disc Medicine in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 69 increasing their positions, 36 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,002% more call options, than puts

Call options by funds: $23.4M | Put options by funds: $1.11M

92% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 36

13% more funds holding in top 10

Funds holding in top 10: 89 (+1)

9% more capital invested

Capital invested by funds: $1.65B → $1.8B (+$155M)

2.46% more ownership

Funds ownership: 95.9%98.37% (+2.5%)

4% less funds holding

Funds holding: 157151 (-6)

16% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 31

Holders
151
Holders Change
-6
Holders Change %
-3.82%
% of All Funds
1.99%
Holding in Top 10
9
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+12.5%
% of All Funds
0.12%
New
26
Increased
69
Reduced
36
Closed
31
Calls
$23.4M
Puts
$1.11M
Net Calls
+$22.3M
Net Calls Change
+$21M
Name Holding Trade Value Shares
Change
Change in
Stake
TWD
151
True Wealth Design
Ohio
$53 -$282 -6 -86%
SCM
152
Silverarc Capital Management
Massachusetts
-$11.7M -236,471 Closed
D.E. Shaw & Co
153
D.E. Shaw & Co
New York
-$10.9M -219,603 Closed
PA
154
Perceptive Advisors
New York
-$7.45M -150,000 Closed
Pictet Asset Management
155
Pictet Asset Management
Switzerland
-$6.47M -130,386 Closed
SCM
156
Suvretta Capital Management
New York
-$3.97M -80,000 Closed
Citadel Advisors
157
Citadel Advisors
Florida
-$2.92M -62,214 Closed
TC
158
TwinBeech Capital
New York
-$2.26M -45,448 Closed
GCM
159
Ghisallo Capital Management
Massachusetts
-$1.24M -25,000 Closed
AI
160
Atom Investors
Texas
-$1.12M -22,561 Closed
EGM
161
Engineers Gate Manager
New York
-$834K -16,810 Closed
AG
162
Algert Global
California
-$811K -16,337 Closed
SG Americas Securities
163
SG Americas Securities
New York
-$711K -14,329 Closed
ACM
164
Aquatic Capital Management
Illinois
-$605K -12,188 Closed
CF
165
Corebridge Financial
Texas
-$555K -11,180 Closed
TI
166
Trexquant Investment
Connecticut
-$425K -8,556 Closed
QT
167
Quantbot Technologies
New York
-$376K -7,565 Closed
SSA
168
Schonfeld Strategic Advisors
New York
-$375K -7,552 Closed
VRS
169
Virginia Retirement Systems
Virginia
-$288K -5,800 Closed
CWM
170
CIBC World Markets
New York
-$251K -5,064 Closed
Verition Fund Management
171
Verition Fund Management
Connecticut
-$212K -4,279 Closed
GCM
172
Graham Capital Management
Connecticut
-$209K -4,217 Closed
ACM
173
Aster Capital Management
United Arab Emirates
-$32.4K -577 Closed
CCM
174
Coldstream Capital Management
Washington
-$2.28K -46 Closed
FFO
175
Fortitude Family Office
Arizona
-$993 -20 Closed

IRON Hedge Fund Activity: Q2 2025 in Review

151 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q2 2025, worth a combined $1.8B — up 9.4% from $1.65B a quarter earlier.

Sellers outnumbered buyers: 31 funds closed out of IRON and 26 opened new positions — a net loss of 5 holders — while 36 trimmed existing stakes and 69 added.

The largest buyer was Woodline Partners, adding an estimated $17.1M. The largest seller was Wellington Management Group, cutting an estimated $42.8M.

  • 151 institutional investors held Disc Medicine (IRON) as of Q2 2025, down from 157 in Q1 2025.
  • Funds reported $1.8B of Disc Medicine stock for Q2 2025, up 9.4% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q2 2025 and 31 closed out, a net change of -5 holders.
  • The largest Disc Medicine buyer in Q2 2025 was Woodline Partners, an estimated $17.1M added.
  • The largest Disc Medicine seller in Q2 2025 was Wellington Management Group, an estimated $42.8M sold.

Based on aggregated 13F filings for Q2 2025.