D.E. Shaw & Co
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D.E. Shaw & Co’s Disc Medicine IRON Stock Holding History

D.E. Shaw & Co’s Portfolio IRON Stock Details IRON Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q2 		– Sell
-219,603
Closed -$10.9M – 4519
2025
Q1 		$10.9M Buy
219,603
+138,413
+170% +$7.7M 0.01% 1327
2024
Q4 		$5.15M Buy
+81,190
New +$4.7M ﹤0.01% 1959
2022
Q1 		– Sell
-642
Closed -$56K – 5732
2021
Q4 		$56K Buy
+642
New +$62.9K ﹤0.01% 5186

Other funds holding IRON

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $790M AUM 223.66% 1-Year Est. Return
FLSM
Frazier Life Sciences Management Palo Alto, California $3.89B AUM 201.1% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

D.E. Shaw & Co's IRON Position: Q2 2025 in Review

D.E. Shaw & Co sold out of Disc Medicine (IRON) in Q2 2025, closing a stake of 219,603 shares — an estimated $10.9M sold.

D.E. Shaw & Co first reported a position in IRON in Q4 2021 and held it in 3 quarters. The position peaked at $10.9M in Q1 2025. 151 funds tracked by Wall St. Rank hold IRON as of Q2 2025.

  • D.E. Shaw & Co reported no remaining Disc Medicine position as of Q2 2025 after selling out during the quarter.
  • D.E. Shaw & Co sold 219,603 Disc Medicine shares in Q2 2025, an estimated $10.9M.
  • D.E. Shaw & Co first reported a position in Disc Medicine in Q4 2021 and held it in 3 quarters.
  • D.E. Shaw & Co's Disc Medicine position peaked at $10.9M in Q1 2025.
  • 151 funds tracked by Wall St. Rank held Disc Medicine as of Q2 2025.

Based on D.E. Shaw & Co's 13F filing for Q2 2025, filed 14 Aug 2025.