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Disc Medicine
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Overview Fund Activity

150 hedge funds and large institutions have $1.8B invested in Disc Medicine in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 69 increasing their positions, 36 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
150
Holders Change
-7
Holders Change %
-4.46%
% of All Funds
2.01%
Holding in Top 10
9
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+12.5%
% of All Funds
0.12%
New
25
Increased
69
Reduced
36
Closed
31
Calls
$23.4M
Puts
$1.11M
Net Calls
+$22.3M
Net Calls Change
+$21M

Top Buyers

1
WP
Woodline Partners
California
$45.9M
2
LGM
Logos Global Management
California
$37.1M
3
FTM
First Turn Management
California
$15.9M
4
BBA
Baker Bros. Advisors
New York
$17.9M
5
SCM
Sio Capital Management
New York
$15.1M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$75.8M
2
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
$30.9M
3
SCM
Silverarc Capital Management
Massachusetts
$0
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
$0
5
PA
Perceptive Advisors
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
SCM
151
Silverarc Capital Management
Massachusetts
– -$11.7M -236,471 Closed
D.E. Shaw & Co
152
D.E. Shaw & Co
New York
– -$10.9M -219,603 Closed
PA
153
Perceptive Advisors
New York
– -$7.45M -150,000 Closed
Pictet Asset Management
154
Pictet Asset Management
Switzerland
– -$6.47M -130,386 Closed
SCM
155
Suvretta Capital Management
New York
– -$3.97M -80,000 Closed
Citadel Advisors
156
Citadel Advisors
Florida
– -$3.09M -62,214 Closed
TC
157
TwinBeech Capital
New York
– -$2.26M -45,448 Closed
GCM
158
Ghisallo Capital Management
Massachusetts
– -$1.24M -25,000 Closed
AI
159
Atom Investors
Texas
– -$1.12M -22,561 Closed
EGM
160
Engineers Gate Manager
New York
– -$834K -16,810 Closed
AG
161
Algert Global
California
– -$811K -16,337 Closed
SG Americas Securities
162
SG Americas Securities
New York
– -$711K -14,329 Closed
ACM
163
Aquatic Capital Management
Illinois
– -$605K -12,188 Closed
CF
164
Corebridge Financial
Texas
– -$555K -11,180 Closed
TI
165
Trexquant Investment
Connecticut
– -$425K -8,556 Closed
QT
166
Quantbot Technologies
New York
– -$376K -7,565 Closed
SSA
167
Schonfeld Strategic Advisors
New York
– -$375K -7,552 Closed
VRS
168
Virginia Retirement Systems
Virginia
– -$288K -5,800 Closed
CWM
169
CIBC World Markets
New York
– -$251K -5,064 Closed
Verition Fund Management
170
Verition Fund Management
Connecticut
– -$212K -4,279 Closed
GCM
171
Graham Capital Management
Connecticut
– -$209K -4,217 Closed
ACM
172
Aster Capital Management
United Arab Emirates
– -$32.4K -577 Closed
CCM
173
Coldstream Capital Management
Washington
– -$2.28K -46 Closed
FFO
174
Fortitude Family Office
Arizona
– -$993 -20 Closed
S
175
SignatureFD
Georgia
– -$894 -18 Closed
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