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Disc Medicine

151 hedge funds and large institutions have $1.8B invested in Disc Medicine in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 69 increasing their positions, 36 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,002% more call options, than puts

Call options by funds: $23.4M | Put options by funds: $1.11M

92% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 36

13% more funds holding in top 10

Funds holding in top 10: 89 (+1)

9% more capital invested

Capital invested by funds: $1.65B → $1.8B (+$155M)

2.46% more ownership

Funds ownership: 95.9%98.37% (+2.5%)

4% less funds holding

Funds holding: 157151 (-6)

16% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 31

Holders
151
Holders Change
-6
Holders Change %
-3.82%
% of All Funds
1.99%
Holding in Top 10
9
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+12.5%
% of All Funds
0.12%
New
26
Increased
69
Reduced
36
Closed
31
Calls
$23.4M
Puts
$1.11M
Net Calls
+$22.3M
Net Calls Change
+$21M
Name Holding Trade Value Shares
Change
Change in
Stake
Susquehanna International Group
51
Susquehanna International Group
Pennsylvania
$4.02M +$237K +5,056 +7%
PSC
52
Patient Square Capital
California
$3.92M -$423K -9,000 -11%
Bank of New York Mellon
53
Bank of New York Mellon
New York
$3.79M +$376K +7,999 +13%
EAM
54
Exome Asset Management
New York
$3.25M -$14.1K -300 -0.5%
ECM
55
ExodusPoint Capital Management
New York
$3.07M +$2.08M +44,380 +327%
NIP
56
Nicholas Investment Partners
California
$2.88M +$2.56M +54,445 New
TD Asset Management
57
TD Asset Management
Ontario, Canada
$2.81M +$498K +10,600 +25%
Manulife (Manufacturers Life Insurance)
58
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.75M +$528K +11,251 +28%
N
59
Nuveen
North Carolina
$2.66M -$2.93M -62,447 -55%
Swiss National Bank
60
Swiss National Bank
Switzerland
$2.27M +$329K +7,000 +19%
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
$1.89M +$170K +3,611 +11%
Aberdeen Group
62
Aberdeen Group
United Kingdom
$1.7M +$1.51M +32,061 New
Rafferty Asset Management
63
Rafferty Asset Management
New York
$1.67M -$120K -2,552 -7%
PHS
64
PFM Health Sciences
California
$1.63M +$1.45M +30,799 New
CCM
65
Catalio Capital Management
New York
$1.62M +$1.44M +30,661 New
BG
66
Bollard Group
Massachusetts
$1.62M +$1.44M +30,635 New
PNC Financial Services Group
67
PNC Financial Services Group
Pennsylvania
$1.33M +$67.6K +1,440 +6%
HP
68
HealthInvest Partners
Sweden
$1.31M +$1.16M +24,652 New
AllianceBernstein
69
AllianceBernstein
Tennessee
$1.28M +$145K +3,080 +15%
Legal & General Group
70
Legal & General Group
United Kingdom
$1.28M +$173K +3,682 +18%
Royal Bank of Canada
71
Royal Bank of Canada
Ontario, Canada
$1.2M +$1.01M +21,401 +1,786%
Wells Fargo
72
Wells Fargo
California
$1.19M -$17.6K -375 -2%
Millennium Management
73
Millennium Management
New York
$1.14M -$4.08M -86,906 -80%
California State Teachers Retirement System (CalSTRS)
74
California State Teachers Retirement System (CalSTRS)
California
$1.07M +$4.6K +98 +0.5%
Voloridge Investment Management
75
Voloridge Investment Management
Florida
$1.04M +$927K +19,726 New

IRON Hedge Fund Activity: Q2 2025 in Review

151 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q2 2025, worth a combined $1.8B — up 9.4% from $1.65B a quarter earlier.

Sellers outnumbered buyers: 31 funds closed out of IRON and 26 opened new positions — a net loss of 5 holders — while 36 trimmed existing stakes and 69 added.

The largest buyer was Woodline Partners, adding an estimated $17.1M. The largest seller was Wellington Management Group, cutting an estimated $42.8M.

  • 151 institutional investors held Disc Medicine (IRON) as of Q2 2025, down from 157 in Q1 2025.
  • Funds reported $1.8B of Disc Medicine stock for Q2 2025, up 9.4% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q2 2025 and 31 closed out, a net change of -5 holders.
  • The largest Disc Medicine buyer in Q2 2025 was Woodline Partners, an estimated $17.1M added.
  • The largest Disc Medicine seller in Q2 2025 was Wellington Management Group, an estimated $42.8M sold.

Based on aggregated 13F filings for Q2 2025.