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Disc Medicine
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Overview Fund Activity

112 hedge funds and large institutions have $1.17B invested in Disc Medicine in 2023 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 41 increasing their positions, 28 reducing their positions, and 10 closing their positions.

Holders
112
Holders Change
+21
Holders Change %
+23.08%
% of All Funds
1.64%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
32
Increased
41
Reduced
28
Closed
10
Calls
$12.4M
Puts
$9.58M
Net Calls
+$2.87M
Net Calls Change
+$8.4M

Top Buyers

1
PBA
1
Paradigm Biocapital Advisors
New York
$138M
2
AllianceBernstein
2
AllianceBernstein
Tennessee
$21M
3
BlackRock
3
BlackRock
New York
$50.2M
4
Pictet Asset Management
4
Pictet Asset Management
Switzerland
$11.3M
5
Morgan Stanley
5
Morgan Stanley
New York
$13M

Top Sellers

1
NHAS
1
Novo Holdings A/S
Denmark
$0
2
O
2
OrbiMed
New York
$98.3M
3
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$43.3M
4
AVLSA
4
Atlas Venture Life Science Advisors
Massachusetts
$148M
5
5VM
5
5AM Venture Management
California
$17M
Name Holding Trade Value Shares
Change 		Shares
Change %
Rafferty Asset Management
51
Rafferty Asset Management
New York
$2.3M -$1.34M -23,269 -37%
Nuveen Asset Management
52
Nuveen Asset Management
Illinois
$1.96M +$801K +13,867 +69%
Bank of America
53
Bank of America
North Carolina
$1.85M -$1.26M -21,863 -41%
Bank of New York Mellon
54
Bank of New York Mellon
New York
$1.76M -$2.66K -46 -0.2%
Barclays
55
Barclays
United Kingdom
$1.64M -$179K -3,097 -10%
Connor, Clark & Lunn Investment Management (CC&L)
56
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.45M +$486K +8,415 +51%
Two Sigma Investments
57
Two Sigma Investments
New York
$1.33M +$797K +13,794 +148%
SSA
58
Schonfeld Strategic Advisors
New York
$1.29M +$557K +9,646 +76%
Jane Street
59
Jane Street
New York
$1.2M +$589K +10,196 +96%
Millennium Management
60
Millennium Management
New York
$1.2M +$1.2M +20,697 New
TD Asset Management
61
TD Asset Management
Ontario, Canada
$1.17M – – –
Manulife (Manufacturers Life Insurance)
62
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.09M +$368K +6,364 +51%
HF
63
HRT Financial
New York
$974K +$974K +16,870 New
Citigroup
64
Citigroup
New York
$963K -$570K -9,866 -37%
AA
65
ALPS Advisors
Colorado
$933K -$43.3K -750 -4%
JPMorgan Chase & Co
66
JPMorgan Chase & Co
New York
$926K +$577K +9,997 +166%
Swiss National Bank
67
Swiss National Bank
Switzerland
$913K -$92.4K -1,600 -9%
VF
68
Virtu Financial
New York
$797K +$797K +13,802 New
UBS Group
69
UBS Group
Switzerland
$787K -$312K -5,394 -28%
RhumbLine Advisers
70
RhumbLine Advisers
Massachusetts
$730K -$74.5K -1,290 -9%
EGM
71
Engineers Gate Manager
New York
$660K +$660K +11,427 New
MAM
72
Martingale Asset Management
Massachusetts
$653K +$80.9K +1,401 +14%
PNC Financial Services Group
73
PNC Financial Services Group
Pennsylvania
$578K +$346K +5,990 +149%
CC
74
Checkpoint Capital
California
$578K +$578K +10,000 New
YIH
75
Y-Intercept (HK)
Hong Kong
$569K +$569K +9,844 New
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3
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