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Ionis Pharmaceuticals
IONS

Overview Fund Activity

358 hedge funds and large institutions have $6.67B invested in Ionis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 81 funds opening new positions, 121 increasing their positions, 107 reducing their positions, and 57 closing their positions.

Holders
358
Holders Change
+19
Holders Change %
+5.6%
% of All Funds
4.81%
Holding in Top 10
12
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+100%
% of All Funds
0.16%
New
81
Increased
121
Reduced
107
Closed
57
Calls
$48.1M
Puts
$26.1M
Net Calls
+$22M
Net Calls Change
+$16M

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$150M
2
Millennium Management
2
Millennium Management
New York
$105M
3
PCH
3
Polar Capital Holdings
United Kingdom
$39.5M
4
Balyasny Asset Management
4
Balyasny Asset Management
Illinois
$30.4M
5
WP
5
Woodline Partners
California
$29M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$251M
2
Citadel Advisors
2
Citadel Advisors
Florida
$59.1M
3
O
3
OrbiMed
New York
$0
4
Invesco
4
Invesco
Georgia
$10.1M
5
CCM
5
Camber Capital Management
Massachusetts
$0
Name Market Value Shares Shares
Change 		Shares
Change %
CWG
51
C WorldWide Group
Denmark
$17.8M 450,000 +50,000 +13%
SSA
52
Schonfeld Strategic Advisors
New York
$17.7M 449,206 -111,153 -20%
GKIM
53
GW&K Investment Management
Massachusetts
$17.7M 448,830 +266,521 +146%
Aberdeen Group
54
Aberdeen Group
United Kingdom
$16.2M 406,694 -39,503 -9%
Legal & General Group
55
Legal & General Group
United Kingdom
$16M 404,366 +65,904 +19%
GLA
56
Great Lakes Advisors
Illinois
$15.8M 399,646 +399,646 New
JPMorgan Chase & Co
57
JPMorgan Chase & Co
New York
$15.6M 394,978 -26,533 -6%
Ameriprise
58
Ameriprise
Minnesota
$14.5M 368,119 +7,931 +2%
Artisan Partners
59
Artisan Partners
Wisconsin
$14M 354,962 +151,784 +75%
Citigroup
60
Citigroup
New York
$13.5M 340,977 -85,503 -20%
SA
61
Sovran Advisors
California
$13.3M 321,913 -6,991 -2%
Point72 Asset Management
62
Point72 Asset Management
Connecticut
$11.6M 292,647 +5,443 +2%
Swiss National Bank
63
Swiss National Bank
Switzerland
$11.4M 288,600 +13,300 +5%
SGA
64
Sector Gamma AS
Norway
$11.3M 285,842 – –
Renaissance Technologies
65
Renaissance Technologies
New York
$10.7M 270,714 +117,200 +76%
PFM
66
Privium Fund Management
Netherlands
$10.7M 267,594 – –
Connor, Clark & Lunn Investment Management (CC&L)
67
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$10.5M 265,793 +136,520 +106%
Invesco
68
Invesco
Georgia
$10.1M 256,235 -618,599 -71%
NL
69
Nuveen LLC
North Carolina
$9.68M 245,085 -63,692 -21%
Corient Private Wealth
70
Corient Private Wealth
Florida
$9.4M 237,931 +798 +0.3%
Verition Fund Management
71
Verition Fund Management
Connecticut
$9.19M 232,687 +180,400 +345%
OIC
72
Orion Investment Company
Missouri
$8.59M 217,370 +2,080 +1%
Raymond James Financial
73
Raymond James Financial
Florida
$8.32M 210,592 +61,902 +42%
Wells Fargo
74
Wells Fargo
California
$8.29M 209,857 -46,376 -18%
California Public Employees Retirement System
75
California Public Employees Retirement System
California
$7.98M 201,993 +10,989 +6%
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