D.E. Shaw & Co’s Ionis Pharmaceuticals IONS Stock Holding History
Bought
Maintained
Sold
| Quarter | Market Value | Status | Shares |
Change in Stake | Trade Value | Portfolio Weight | Portfolio Position | |
|---|---|---|---|---|---|---|---|---|
|
2026
Q1 | $32.3M | Buy |
429,599
+96,796
| +29% | +$7.64M | 0.02% | 888 |
|
|
2025
Q4 | $26.3M | Sell |
332,803
-298,135
| -47% | -$22.4M | 0.01% | 1069 |
|
|
2025
Q3 | $41.3M | Buy |
+630,938
| New | +$30.8M | 0.02% | 753 |
|
|
2025
Q1 | – | Sell |
-23,123
| Closed | -$808K | – | 4475 |
|
|
2024
Q4 | $808K | Sell |
23,123
-121,968
| -84% | -$4.56M | ﹤0.01% | 3333 |
|
|
2024
Q3 | $5.81M | Sell |
145,091
-45,690
| -24% | -$2.13M | 0.01% | 1821 |
|
|
2024
Q2 | $9.09M | Buy |
190,781
+30,299
| +19% | +$1.24M | 0.01% | 1396 |
|
|
2024
Q1 | $6.96M | Buy |
160,482
+41,324
| +35% | +$1.97M | 0.01% | 1648 |
|
|
2023
Q4 | $6.03M | Sell |
119,158
-242,887
| -67% | -$11.6M | 0.01% | 1759 |
|
|
2023
Q3 | $16.4M | Buy |
362,045
+165,832
| +85% | +$6.84M | 0.02% | 964 |
|
|
2023
Q2 | $8.05M | Buy |
196,213
+109,562
| +126% | +$4.21M | 0.01% | 1514 |
|
|
2023
Q1 | $3.1M | Sell |
86,651
-212,580
| -71% | -$7.98M | ﹤0.01% | 2353 |
|
|
2022
Q4 | $11.3M | Buy |
299,231
+89,786
| +43% | +$3.78M | 0.01% | 1335 |
|
|
2022
Q3 | $9.26M | Buy |
209,445
+82,824
| +65% | +$3.49M | 0.01% | 1423 |
|
|
2022
Q2 | $4.69M | Buy |
+126,621
| New | +$4.77M | 0.01% | 2208 |
|
|
2022
Q1 | – | Sell |
-160,659
| Closed | -$4.89M | – | 5729 |
|
|
2021
Q4 | $4.89M | Buy |
160,659
+34,553
| +27% | +$1.09M | ﹤0.01% | 2404 |
|
|
2021
Q3 | $4.23M | Buy |
126,106
+51,440
| +69% | +$1.94M | ﹤0.01% | 2274 |
|
|
2021
Q2 | $2.98M | Buy |
74,666
+66,560
| +821% | +$2.61M | ﹤0.01% | 2540 |
|
|
2021
Q1 | $364K | Sell |
8,106
-5,311
| -40% | -$296K | ﹤0.01% | 3636 |
|
|
2020
Q4 | $759K | Sell |
13,417
-209,732
| -94% | -$10.5M | ﹤0.01% | 3194 |
|
|
2020
Q3 | $10.6M | Buy |
223,149
+110,277
| +98% | +$6.13M | 0.01% | 1209 |
|
|
2020
Q2 | $6.66M | Buy |
112,872
+87,876
| +352% | +$4.89M | 0.01% | 1452 |
|
|
2020
Q1 | $1.18M | Sell |
24,996
-524,362
| -95% | -$29.2M | ﹤0.01% | 2607 |
|
|
2019
Q4 | $33.2M | Sell |
549,358
-280,132
| -34% | -$16.7M | 0.04% | 567 |
|
|
2019
Q3 | $49.7M | Buy |
829,490
+96,531
| +13% | +$6.29M | 0.06% | 391 |
|
|
2019
Q2 | $47.1M | Buy |
732,959
+175,768
| +32% | +$12.4M | 0.06% | 397 |
|
|
2019
Q1 | $45.2M | Buy |
557,191
+146,492
| +36% | +$9.45M | 0.06% | 409 |
|
|
2018
Q4 | $22.2M | Buy |
410,699
+294,184
| +252% | +$15M | 0.03% | 669 |
|
|
2018
Q3 | $6.01M | Buy |
116,515
+104,215
| +847% | +$4.9M | 0.01% | 1452 |
|
|
2018
Q2 | $513K | Sell |
12,300
-12,462
| -50% | -$552K | ﹤0.01% | 3103 |
|
|
2018
Q1 | $1.09M | Sell |
24,762
-54,723
| -69% | -$2.78M | ﹤0.01% | 2436 |
|
|
2017
Q4 | $4M | Buy |
79,485
+12,917
| +19% | +$708K | 0.01% | 1644 |
|
|
2017
Q3 | $3.38M | Buy |
66,568
+12,704
| +24% | +$665K | 0.01% | 1672 |
|
|
2017
Q2 | $2.74M | Buy |
53,864
+33,048
| +159% | +$1.54M | ﹤0.01% | 1772 |
|
|
2017
Q1 | $837K | Sell |
20,816
-45,788
| -69% | -$2.06M | ﹤0.01% | 2420 |
|
|
2016
Q4 | $3.19M | Buy |
66,604
+32,334
| +94% | +$1.28M | 0.01% | 1657 |
|
|
2016
Q3 | $1.26M | Sell |
34,270
-8,346
| -20% | -$261K | ﹤0.01% | 2246 |
|
|
2016
Q2 | $993K | Buy |
+42,616
| New | +$1.37M | ﹤0.01% | 2410 |
|
|
2016
Q1 | – | Sell |
-32,224
| Closed | -$1.31M | – | 3593 |
|
|
2015
Q4 | $2M | Buy |
32,224
+18,401
| +133% | +$993K | ﹤0.01% | 2128 |
|
|
2015
Q3 | $559K | Sell |
13,823
-34,746
| -72% | -$1.8M | ﹤0.01% | 2985 |
|
|
2015
Q2 | $2.79M | Buy |
48,569
+12,492
| +35% | +$794K | ﹤0.01% | 1930 |
|
|
2015
Q1 | $2.3M | Sell |
36,077
-1,748
| -5% | -$119K | ﹤0.01% | 1900 |
|
|
2014
Q4 | $2.33M | Sell |
37,825
-4,700
| -11% | -$232K | ﹤0.01% | 2151 |
|
|
2014
Q3 | $1.65M | Buy |
42,525
+15,497
| +57% | +$549K | ﹤0.01% | 2380 |
|
|
2014
Q2 | $931K | Buy |
+27,028
| New | +$851K | ﹤0.01% | 3009 |
|
|
2013
Q3 | – | Sell |
-25,227
| Closed | -$754K | – | 4367 |
|
|
2013
Q2 | $678K | Buy |
+25,227
| New | +$536K | ﹤0.01% | 3013 |
|
Other funds holding IONS
VPM
VCM
D.E. Shaw & Co's IONS Position: Q1 2026 in Review
D.E. Shaw & Co increased its Ionis Pharmaceuticals (IONS) stake by 29% in Q1 2026, buying an estimated $7.64M and bringing the position to 429,599 shares worth $32.3M. The position accounts for 0.02% of the portfolio, ranked #888.
D.E. Shaw & Co first reported a position in IONS in Q2 2013 and has held it in 45 quarters since. The position peaked at $49.7M in Q3 2019. 493 funds tracked by Wall St. Rank hold IONS as of Q1 2026.
- D.E. Shaw & Co held 429,599 shares of Ionis Pharmaceuticals worth $32.3M as of Q1 2026.
- D.E. Shaw & Co bought 96,796 Ionis Pharmaceuticals shares in Q1 2026, an estimated $7.64M.
- Ionis Pharmaceuticals made up 0.02% of D.E. Shaw & Co's portfolio in Q1 2026, its #888 holding.
- D.E. Shaw & Co first reported a position in Ionis Pharmaceuticals in Q2 2013 and has held it in 45 quarters since.
- D.E. Shaw & Co's Ionis Pharmaceuticals position peaked at $49.7M in Q3 2019.
- 493 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.
Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.