|
1
|
Primecap Management
Pasadena,
California
|
$210M
|
-$2.03M
|
-94,523
|
-0.7%
|
|
|
2
|
|
$142M
|
+$53.7M
|
+2,500,000
|
+37%
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$136M
|
+$482K
|
+22,442
|
+0.3%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$108M
|
+$3.88M
|
+180,859
|
+3%
|
|
|
5
|
|
$106M
|
-$2.23M
|
-103,651
|
-1%
|
|
|
6
|
Palo Alto Investors
Palo Alto,
California
|
$86.1M
|
-$12.8M
|
-594,142
|
-10%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$67.9M
|
–
|
–
|
–
|
|
|
8
|
Consonance Capital Management
New York
|
$51.3M
|
-$21.5M
|
-1,001,657
|
-23%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$38.7M
|
+$662K
|
+30,834
|
+1%
|
|
|
10
|
MPM BioImpact
Boston,
Massachusetts
|
$36.2M
|
–
|
–
|
–
|
|
|
11
|
|
$35.7M
|
+$1.07M
|
+50,000
|
+2%
|
|
|
12
|
Victory Capital Management
San Antonio,
Texas
|
$33.8M
|
-$10.1M
|
-468,584
|
-18%
|
|
|
13
|
Fidelity Investments
Boston,
Massachusetts
|
$31.3M
|
-$4.72M
|
-219,808
|
-10%
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$30.3M
|
-$2.04M
|
-95,000
|
-5%
|
|
|
15
|
Janus Henderson Group
London,
|
$30.2M
|
+$29.7M
|
+1,383,330
|
+245%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$21.4M
|
-$450K
|
-20,943
|
-1%
|
|
|
17
|
|
$20.8M
|
+$9.82M
|
+457,287
|
+52%
|
|
|
18
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$19.6M
|
-$7.19M
|
-334,749
|
-21%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$18M
|
+$2.15M
|
+100,152
|
+9%
|
|
|
20
|
Dimensional Fund Advisors
Austin,
Texas
|
$16.2M
|
-$167K
|
-7,755
|
-0.7%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$14.9M
|
+$252K
|
+11,720
|
+1%
|
|
|
22
|
Burrage Capital Management
Boston,
Massachusetts
|
$12.5M
|
-$1.54M
|
-71,821
|
-7%
|
|
|
23
|
Foresite Capital Management III
Larkspur,
California
|
$11.1M
|
+$567K
|
+26,385
|
+4%
|
|
|
24
|
|
$9.92M
|
+$6.53M
|
+303,829
|
+90%
|
|
|
25
|
VOYA Investment Management
Atlanta,
Georgia
|
$8.59M
|
+$3.46M
|
+160,990
|
+41%
|
|
