|
1
|
Primecap Management
Pasadena,
California
|
$336M
|
+$32.4M
|
+2,184,777
|
+19%
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$215M
|
+$1.62M
|
+109,100
|
+1%
|
|
|
3
|
|
$170M
|
+$1.77M
|
+119,176
|
+2%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$167M
|
-$5.03M
|
-339,060
|
-5%
|
|
|
5
|
|
$164M
|
+$99M
|
+6,666,667
|
New
|
|
|
6
|
Palo Alto Investors
Palo Alto,
California
|
$151M
|
-$3.1M
|
-208,714
|
-3%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$108M
|
–
|
–
|
–
|
|
|
8
|
Consonance Capital Management
New York
|
$106M
|
+$4.92M
|
+331,521
|
+8%
|
|
|
9
|
Victory Capital Management
San Antonio,
Texas
|
$65.1M
|
+$6.99M
|
+470,980
|
+22%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$60.6M
|
-$5.82M
|
-392,233
|
-14%
|
|
|
11
|
MPM BioImpact
Boston,
Massachusetts
|
$57.4M
|
+$34.6M
|
+2,331,534
|
New
|
|
|
12
|
|
$55.4M
|
+$11.1M
|
+750,000
|
+50%
|
|
|
13
|
Fidelity Investments
Boston,
Massachusetts
|
$55M
|
-$6.38M
|
-429,490
|
-16%
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$50.4M
|
+$2.97M
|
+199,900
|
+11%
|
|
|
15
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$39.4M
|
-$77.3K
|
-5,207
|
-0.3%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$34.5M
|
+$20.4M
|
+1,372,023
|
+4,416%
|
|
|
17
|
Opaleye Management
Boston,
Massachusetts
|
$34.1M
|
+$285K
|
+19,200
|
+1%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$26.2M
|
+$974K
|
+65,639
|
+7%
|
|
|
19
|
Dimensional Fund Advisors
Austin,
Texas
|
$25.9M
|
+$3.17M
|
+213,602
|
+25%
|
|
|
20
|
Burrage Capital Management
Boston,
Massachusetts
|
$23.8M
|
+$14.3M
|
+965,519
|
New
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$23.4M
|
-$420K
|
-28,284
|
-3%
|
|
|
22
|
|
$21.8M
|
–
|
–
|
–
|
|
|
23
|
Foresite Capital Management III
Larkspur,
California
|
$16.9M
|
-$4.61M
|
-310,851
|
-31%
|
|
|
24
|
Foresite Capital Management II
Larkspur,
California
|
$14.5M
|
-$13.3M
|
-897,140
|
-60%
|
|
|
25
|
Janus Henderson Group
London,
|
$13.9M
|
+$8.38M
|
+564,501
|
New
|
|
