|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$83.6M
|
+$3.43M
|
+308,014
|
+4%
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$66.7M
|
-$25.6K
|
-2,300
|
-0%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$64.1M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$28.9M
|
+$908K
|
+81,472
|
+3%
|
|
|
5
|
Palo Alto Investors
Palo Alto,
California
|
$27.8M
|
+$623K
|
+55,902
|
+2%
|
|
|
6
|
Jennison Associates
New York
|
$18.2M
|
+$143K
|
+12,863
|
+0.7%
|
|
|
7
|
MPM Asset Management
Boston,
Massachusetts
|
$17.7M
|
–
|
–
|
–
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$17.3M
|
-$103K
|
-9,202
|
-0.5%
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$12.3M
|
–
|
–
|
–
|
|
|
10
|
Foresite Capital Management II
Larkspur,
California
|
$12.2M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$10.3M
|
-$269K
|
-24,157
|
-2%
|
|
|
12
|
|
$9.95M
|
-$2.33M
|
-209,298
|
-18%
|
|
|
13
|
Millennium Management
New York
|
$9.58M
|
+$2.28M
|
+204,492
|
+28%
|
|
|
14
|
BlackRock Institutional Trust
San Francisco,
California
|
$8.48M
|
+$27.2K
|
+2,443
|
+0.3%
|
|
|
15
|
EcoR1 Capital
San Francisco,
California
|
$7.73M
|
-$9.41M
|
-843,854
|
-53%
|
|
|
16
|
CQS Cayman
Camana Bay, Grand Cayman,
Cayman Islands
|
$6.5M
|
+$7.08M
|
+635,000
|
New
|
|
|
17
|
Deerfield Management
New York
|
$6.37M
|
+$6.94M
|
+622,299
|
New
|
|
|
18
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$6.12M
|
+$94.8K
|
+8,500
|
+1%
|
|
|
19
|
Foresite Capital Management III
Larkspur,
California
|
$5.24M
|
+$390K
|
+35,000
|
+7%
|
|
|
20
|
|
$5.04M
|
–
|
–
|
–
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$4.69M
|
-$82.9K
|
-7,434
|
-2%
|
|
|
22
|
Tekla Capital Management
Boston,
Massachusetts
|
$4.1M
|
–
|
–
|
–
|
|
|
23
|
|
$3.48M
|
-$2.29M
|
-205,000
|
-38%
|
|
|
24
|
Spark Investment Management
New York
|
$3.39M
|
–
|
–
|
–
|
|
|
25
|
Geode Capital Management
Boston,
Massachusetts
|
$3.08M
|
+$322K
|
+28,835
|
+11%
|
|
