|
1
|
Primecap Management
Pasadena,
California
|
$58.9M
|
-$858K
|
-112,400
|
-1%
|
|
|
2
|
Palo Alto Investors
Palo Alto,
California
|
$42.7M
|
+$221K
|
+28,916
|
+0.4%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$42.4M
|
+$3.18M
|
+416,667
|
+6%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$40.9M
|
+$33.5M
|
+4,389,089
|
+195%
|
|
|
5
|
|
$32M
|
+$6.34M
|
+830,815
|
+19%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$22.4M
|
-$7.08M
|
-927,035
|
-20%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$21.4M
|
-$1.48M
|
-193,825
|
-5%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$15.8M
|
+$2.74M
|
+358,154
|
+16%
|
|
|
9
|
Jennison Associates
New York
|
$11.6M
|
-$2.47M
|
-324,042
|
-15%
|
|
|
10
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$9.9M
|
+$2.8M
|
+366,247
|
+30%
|
|
|
11
|
Foresite Capital Management II
Larkspur,
California
|
$9.6M
|
+$958K
|
+125,500
|
+9%
|
|
|
12
|
VOYA Investment Management
Atlanta,
Georgia
|
$8.52M
|
-$3.09M
|
-404,287
|
-23%
|
|
|
13
|
|
$6.96M
|
–
|
–
|
–
|
|
|
14
|
Opaleye Management
Boston,
Massachusetts
|
$6.93M
|
+$7.06M
|
+925,000
|
+463%
|
|
|
15
|
Foresite Capital Management III
Larkspur,
California
|
$6.15M
|
+$615K
|
+80,500
|
+9%
|
|
|
16
|
Millennium Management
New York
|
$5.04M
|
+$5.25M
|
+687,047
|
+521%
|
|
|
17
|
Sphera Funds Management
Tel Aviv,
Israel
|
$4.62M
|
+$2.67M
|
+350,000
|
+88%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$4.57M
|
+$544K
|
+71,260
|
+11%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$4.09M
|
+$935K
|
+122,457
|
+23%
|
|
|
20
|
Marshall Wace
London,
United Kingdom
|
$3.58M
|
+$2.02M
|
+264,052
|
+83%
|
|
|
21
|
Sofinnova Investments
Menlo Park,
California
|
$3.47M
|
+$2.08M
|
+272,337
|
+93%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.43M
|
+$2.42M
|
+317,157
|
+133%
|
|
|
23
|
|
$2.93M
|
-$379K
|
-49,667
|
-9%
|
|
|
24
|
Tekla Capital Management
Boston,
Massachusetts
|
$2.38M
|
-$760K
|
-99,453
|
-20%
|
|
|
25
|
|
$2.32M
|
+$110K
|
+14,400
|
+4%
|
|
