|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$80.4M
|
–
|
–
|
–
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$64.2M
|
+$82.2K
|
+9,000
|
+0.1%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$61.6M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$29.1M
|
+$1.21M
|
+132,285
|
+5%
|
|
|
5
|
Palo Alto Investors
Palo Alto,
California
|
$27.7M
|
+$942K
|
+103,159
|
+4%
|
|
|
6
|
BlackRock Fund Advisors
San Francisco,
California
|
$17.7M
|
+$999K
|
+109,415
|
+6%
|
|
|
7
|
Jennison Associates
New York
|
$17.2M
|
-$264K
|
-28,940
|
-2%
|
|
|
8
|
MPM Asset Management
Boston,
Massachusetts
|
$17M
|
–
|
–
|
–
|
|
|
9
|
Foresite Capital Management II
Larkspur,
California
|
$15.2M
|
+$3.21M
|
+351,123
|
+29%
|
|
|
10
|
Franklin Resources
San Mateo,
California
|
$11.8M
|
–
|
–
|
–
|
|
|
11
|
VOYA Investment Management
Atlanta,
Georgia
|
$8.64M
|
+$7.87M
|
+861,725
|
+5,387%
|
|
|
12
|
BlackRock Institutional Trust
San Francisco,
California
|
$8.54M
|
+$361K
|
+39,585
|
+5%
|
|
|
13
|
|
$8.37M
|
-$1.11M
|
-121,500
|
-13%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$7.17M
|
-$2.5M
|
-274,283
|
-27%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$6.32M
|
+$411K
|
+45,000
|
+8%
|
|
|
16
|
CQS Cayman
Camana Bay, Grand Cayman,
Cayman Islands
|
$6.24M
|
-$6.39K
|
-700
|
-0.1%
|
|
|
17
|
Foresite Capital Management III
Larkspur,
California
|
$6.02M
|
+$913K
|
+100,000
|
+20%
|
|
|
18
|
|
$4.63M
|
–
|
–
|
–
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$4.46M
|
-$50.4K
|
-5,522
|
-1%
|
|
|
20
|
Tekla Capital Management
Boston,
Massachusetts
|
$3.94M
|
–
|
–
|
–
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$2.91M
|
-$49.3K
|
-5,403
|
-2%
|
|
|
22
|
|
$2.9M
|
-$411K
|
-45,000
|
-13%
|
|
|
23
|
Deerfield Management
New York
|
$2.87M
|
-$3.02M
|
-331,120
|
-53%
|
|
|
24
|
Eventide Asset Management
Boston,
Massachusetts
|
$2.71M
|
–
|
–
|
–
|
|
|
25
|
Millennium Management
New York
|
$2.7M
|
-$6.03M
|
-660,543
|
-71%
|
|
