|
1
|
Primecap Management
Pasadena,
California
|
$131M
|
+$21.6M
|
+1,384,900
|
+17%
|
|
|
2
|
Palo Alto Investors
Palo Alto,
California
|
$93.6M
|
+$172K
|
+11,083
|
+0.2%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$87.5M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$82.6M
|
-$20.7M
|
-1,328,126
|
-18%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$60.8M
|
+$2.62M
|
+168,587
|
+4%
|
|
|
6
|
|
$58.3M
|
+$6.33M
|
+406,541
|
+10%
|
|
|
7
|
Jennison Associates
New York
|
$29.6M
|
+$572K
|
+36,762
|
+2%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$27.5M
|
+$3.61M
|
+231,862
|
+13%
|
|
|
9
|
Redmile Group
San Francisco,
California
|
$27.4M
|
+$146K
|
+9,400
|
+0.5%
|
|
|
10
|
Deerfield Management
New York
|
$22.2M
|
+$10.6M
|
+678,030
|
+71%
|
|
|
11
|
Foresite Capital Management II
Larkspur,
California
|
$19.9M
|
-$1.4M
|
-89,893
|
-6%
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$16.8M
|
-$525K
|
-33,747
|
-3%
|
|
|
13
|
VOYA Investment Management
Atlanta,
Georgia
|
$16M
|
+$8.97M
|
+576,436
|
+95%
|
|
|
14
|
Foresite Capital Management III
Larkspur,
California
|
$12.7M
|
-$896K
|
-57,593
|
-6%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$11M
|
+$3.55M
|
+228,405
|
+39%
|
|
|
16
|
|
$10.9M
|
+$1.96M
|
+126,182
|
+19%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$8.82M
|
+$1.09M
|
+70,281
|
+12%
|
|
|
18
|
|
$8M
|
+$6.49M
|
+416,939
|
+240%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$6.95M
|
+$548K
|
+35,186
|
+7%
|
|
|
20
|
Tekla Capital Management
Boston,
Massachusetts
|
$6.58M
|
–
|
–
|
–
|
|
|
21
|
Peregrine Capital Management
Minneapolis,
Minnesota
|
$6.11M
|
-$410K
|
-26,322
|
-6%
|
|
|
22
|
Sphera Funds Management
Tel Aviv,
Israel
|
$4.16M
|
+$4.78M
|
+307,154
|
New
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$3.74M
|
+$182K
|
+11,693
|
+4%
|
|
|
24
|
Opaleye Management
Boston,
Massachusetts
|
$3.73M
|
+$3.19M
|
+205,000
|
+293%
|
|
|
25
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$3.3M
|
+$27.1K
|
+1,740
|
+0.7%
|
|
