|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$79.5M
|
–
|
–
|
–
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$77.7M
|
+$315K
|
+15,600
|
+0.3%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$66.2M
|
–
|
–
|
–
|
|
|
4
|
Palo Alto Investors
Palo Alto,
California
|
$27.2M
|
+$41.5M
|
+2,054,373
|
+3,353%
|
|
|
5
|
MPM Asset Management
Boston,
Massachusetts
|
$22.2M
|
-$1.04M
|
-51,412
|
-3%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$21.8M
|
+$1.6M
|
+79,053
|
+5%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$20.9M
|
-$919K
|
-45,541
|
-3%
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$19.2M
|
-$3.9M
|
-193,100
|
-11%
|
|
|
9
|
BlackRock Fund Advisors
San Francisco,
California
|
$16.4M
|
+$1.12M
|
+55,334
|
+5%
|
|
|
10
|
Foresite Capital Management II
Larkspur,
California
|
$13M
|
+$2.26M
|
+111,932
|
+12%
|
|
|
11
|
|
$8.41M
|
+$876K
|
+43,386
|
+7%
|
|
|
12
|
Balyasny Asset Management
Chicago,
Illinois
|
$8.39M
|
-$4.22M
|
-209,155
|
-24%
|
|
|
13
|
BlackRock Institutional Trust
San Francisco,
California
|
$7.36M
|
+$4.14M
|
+205,060
|
+56%
|
|
|
14
|
|
$5.56M
|
+$24.9K
|
+1,236
|
+0.3%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$4.16M
|
+$2.28M
|
+112,985
|
+54%
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$3.99M
|
+$70.6K
|
+3,500
|
+1%
|
|
|
17
|
|
$3.98M
|
+$5.89M
|
+291,683
|
+1,611%
|
|
|
18
|
Cormorant Asset Management
Boston,
Massachusetts
|
$3.42M
|
–
|
–
|
–
|
|
|
19
|
Tekla Capital Management
Boston,
Massachusetts
|
$3.3M
|
+$1.14M
|
+56,700
|
+28%
|
|
|
20
|
Jennison Associates
New York
|
$3.26M
|
+$31.3K
|
+1,551
|
+0.6%
|
|
|
21
|
Spark Investment Management
New York
|
$3M
|
+$4.71M
|
+233,600
|
New
|
|
|
22
|
Baker Bros. Advisors
New York
|
$2.99M
|
–
|
–
|
–
|
|
|
23
|
RA Capital Management
Boston,
Massachusetts
|
$2.92M
|
+$4.58M
|
+227,092
|
New
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$2.09M
|
+$54.2K
|
+2,685
|
+2%
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.01M
|
-$121K
|
-6,000
|
-4%
|
|
