|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$99M
|
–
|
–
|
–
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$84M
|
-$11.8M
|
-793,578
|
-13%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$82.5M
|
–
|
–
|
–
|
|
|
4
|
Palo Alto Investors
Palo Alto,
California
|
$42.6M
|
+$8.08M
|
+545,341
|
+26%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$27.9M
|
+$638K
|
+43,037
|
+3%
|
|
|
6
|
MPM Asset Management
Boston,
Massachusetts
|
$27.7M
|
–
|
–
|
–
|
|
|
7
|
BlackRock Fund Advisors
San Francisco,
California
|
$19.2M
|
-$1.22M
|
-82,176
|
-6%
|
|
|
8
|
Foresite Capital Management II
Larkspur,
California
|
$18.6M
|
+$2.22M
|
+150,000
|
+15%
|
|
|
9
|
Jennison Associates
New York
|
$14.3M
|
+$9.49M
|
+640,245
|
+252%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$14M
|
-$11.2M
|
-752,732
|
-46%
|
|
|
11
|
EcoR1 Capital
San Francisco,
California
|
$11.2M
|
-$11.8M
|
-793,800
|
-53%
|
|
|
12
|
|
$9.54M
|
-$867K
|
-58,514
|
-9%
|
|
|
13
|
BlackRock Institutional Trust
San Francisco,
California
|
$9.48M
|
+$283K
|
+19,097
|
+3%
|
|
|
14
|
Foresite Capital Management III
Larkspur,
California
|
$7.4M
|
+$6.84M
|
+461,651
|
New
|
|
|
15
|
|
$6.93M
|
–
|
–
|
–
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$5.93M
|
+$890K
|
+60,000
|
+19%
|
|
|
17
|
|
$5.33M
|
+$4.93M
|
+332,500
|
New
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$5.31M
|
+$110K
|
+7,414
|
+2%
|
|
|
19
|
|
$4.69M
|
-$253K
|
-17,055
|
-6%
|
|
|
20
|
Cormorant Asset Management
Boston,
Massachusetts
|
$4.26M
|
–
|
–
|
–
|
|
|
21
|
Baker Bros. Advisors
New York
|
$3.72M
|
–
|
–
|
–
|
|
|
22
|
Spark Investment Management
New York
|
$3.48M
|
-$245K
|
-16,500
|
-7%
|
|
|
23
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.9M
|
+$371K
|
+25,000
|
+16%
|
|
|
24
|
California Public Employees Retirement System
Sacramento,
California
|
$2.72M
|
+$2.52M
|
+170,000
|
New
|
|
|
25
|
Geode Capital Management
Boston,
Massachusetts
|
$2.64M
|
+$33.1K
|
+2,234
|
+1%
|
|
