|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$120M
|
-$15.7M
|
-1,175,788
|
-14%
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$112M
|
-$26.6K
|
-2,000
|
-0%
|
|
|
3
|
NEA Management Company
Timonium,
Maryland
|
$107M
|
–
|
–
|
–
|
|
|
4
|
Palo Alto Investors
Palo Alto,
California
|
$82.2M
|
+$23.4M
|
+1,755,255
|
+58%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$55.2M
|
+$1.85M
|
+139,066
|
+5%
|
|
|
6
|
|
$55.2M
|
+$42.8M
|
+3,214,076
|
+70,561%
|
|
|
7
|
Jennison Associates
New York
|
$33.2M
|
–
|
–
|
–
|
|
|
8
|
Foresite Capital Management II
Larkspur,
California
|
$26.5M
|
+$220K
|
+16,481
|
+1%
|
|
|
9
|
Deerfield Management
New York
|
$24.2M
|
-$2.5M
|
-187,453
|
-12%
|
|
|
10
|
Franklin Resources
San Mateo,
California
|
$19.9M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$19M
|
+$228K
|
+17,088
|
+2%
|
|
|
12
|
Foresite Capital Management III
Larkspur,
California
|
$11.7M
|
+$1.02M
|
+76,683
|
+13%
|
|
|
13
|
|
$10.6M
|
+$1.68M
|
+125,960
|
+26%
|
|
|
14
|
CQS Cayman
Camana Bay, Grand Cayman,
Cayman Islands
|
$10.5M
|
-$266K
|
-20,000
|
-3%
|
|
|
15
|
Ghost Tree Capital
New York
|
$10.3M
|
+$1.66M
|
+125,000
|
+26%
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$9.78M
|
–
|
–
|
–
|
|
|
17
|
Oracle Investment Management
Greenwich,
Connecticut
|
$8.87M
|
+$6.89M
|
+516,940
|
New
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$8.65M
|
+$50.2K
|
+3,772
|
+0.8%
|
|
|
19
|
VOYA Investment Management
Atlanta,
Georgia
|
$8.33M
|
-$4.97M
|
-372,928
|
-43%
|
|
|
20
|
|
$8.32M
|
+$2.8M
|
+210,000
|
+76%
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$6.21M
|
-$506K
|
-38,000
|
-10%
|
|
|
22
|
|
$6.1M
|
-$2.33M
|
-174,836
|
-33%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$5.79M
|
+$204K
|
+15,299
|
+5%
|
|
|
24
|
Eventide Asset Management
Boston,
Massachusetts
|
$4.72M
|
–
|
–
|
–
|
|
|
25
|
Baker Bros. Advisors
New York
|
$3.99M
|
–
|
–
|
–
|
|
