Simplex Trading’s Praxis Precision Medicines PRAX Stock Holding History

Simplex Trading’s Portfolio PRAX Stock Details PRAX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$3.96M	Buy	+12,300	New	+$3.81M	﹤0.01%	1282
2025 Q4	–	Sell	-24,600	Closed	-$1.3M	–	9751
2025 Q3	$1.3M	Sell	24,600 -16,000	-39%	-$776K	﹤0.01%	2776
2025 Q2	$1.71M	Sell	40,600 -5,500	-12%	-$209K	﹤0.01%	2252
2025 Q1	$1.75M	Sell	46,100 -3,200	-6%	-$200K	﹤0.01%	2167
2024 Q4	$3.79M	Buy	49,300 +33,300	+208%	+$2.41M	﹤0.01%	1676
2024 Q3	$920K	Buy	16,000 +15,800	+7,900%	+$854K	﹤0.01%	2996
2024 Q2	$8K	Sell	200 -800	-80%	-$37.8K	﹤0.01%	7605
2024 Q1	$61K	Buy	+1,000	New	+$44.9K	﹤0.01%	6089
2022 Q3	–	Sell	-840	Closed	-$30K	–	10671
2022 Q2	$30K	Buy	+840	New	+$89.7K	﹤0.01%	7160

Other funds holding PRAX

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

OAG

Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

CAM

Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return

Simplex Trading's PRAX Position: Q1 2026 in Review

Simplex Trading opened a new position in Praxis Precision Medicines (PRAX) in Q1 2026: 1,660 shares worth $535K. The stake represents ﹤0.01% of the portfolio and ranks #3170 among its holdings. This is a return to the name: Simplex Trading previously reported a position in PRAX as recently as Q3 2025.

Simplex Trading first reported a position in PRAX in Q4 2021 and has held it in 13 quarters since. The position peaked at $1.3M in Q4 2024. 289 funds tracked by Wall St. Rank hold PRAX as of Q1 2026.

Simplex Trading held 1,660 shares of Praxis Precision Medicines worth $535K as of Q1 2026.
Praxis Precision Medicines was a new Simplex Trading position in Q1 2026.
Praxis Precision Medicines made up ﹤0.01% of Simplex Trading's portfolio in Q1 2026, its #3170 holding.
Simplex Trading first reported a position in Praxis Precision Medicines in Q4 2021 and has held it in 13 quarters since.
Simplex Trading's Praxis Precision Medicines position peaked at $1.3M in Q4 2024.
289 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.