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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+23.39%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$1.47B
AUM Growth
+$375M
Cap. Flow
+$157M
Cap. Flow %
10.72%
Top 10 Hldgs %
58.22%
Holding
55
New
7
Increased
25
Reduced
10
Closed
4

Top Buys

Rank Stock Value
1
PRQR icon
ProQR Therapeutics
PRQR
+$48.9M
2
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$33.2M
3
BMY icon
Bristol-Myers Squibb
BMY
+$28.6M
4
PTCT icon
PTC Therapeutics
PTCT
+$19.9M
5
MYOK
MyoKardia, Inc. Common Stock
MYOK
+$19M

Top Sells

Rank Stock Value
1
ARWR icon
Arrowhead Research
ARWR
+$62.5M
2
RGNX icon
Regenxbio
RGNX
+$29.7M
3
SAGE
Sage Therapeutics
SAGE
+$15.9M
4
ASMB icon
Assembly Biosciences
ASMB
+$15.5M
5
QURE icon
uniQure
QURE
+$13.7M

Sector Composition

Rank Sector Weight
1 Healthcare 91.68%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KIDS icon
26
OrthoPediatrics
KIDS
$573M
$18.9M 1.29%
428,142
+203,142
+90% +$7.73M
WVE icon
27
Wave Life Sciences
WVE
$1.17B
$17M 1.16%
+436,777
New +$17.7M
PRNB
28
DELISTED
Principia Biopharma Inc. Common Stock
PRNB
$15.5M 1.06%
455,948
-100,000
-18% -$3.18M
TBIO
29
DELISTED
Translate Bio, Inc. Common Stock
TBIO
$13.8M 0.94%
+1,352,970
New +$10.4M
ARVN icon
30
Arvinas
ARVN
$542M
$13.5M 0.92%
+916,514
New +$16.3M
JNJ icon
31
Johnson & Johnson
JNJ
$621B
$11.8M 0.81%
84,614
+4,031
+5% +$540K
CTMX icon
32
CytomX Therapeutics
CTMX
$729M
$10.4M 0.71%
965,252
+56,666
+6% +$838K
QURE icon
33
uniQure
QURE
$3.07B
$9.19M 0.63%
154,058
-307,779
-67% -$13.7M
MYGN icon
34
Myriad Genetics
MYGN
$301M
$8.88M 0.61%
+267,491
New +$8.14M
AXSM icon
35
Axsome Therapeutics
AXSM
$11B
$8.48M 0.58%
+595,635
New +$5.53M
ODT
36
DELISTED
Odonate Therapeutics, Inc. Common Stock
ODT
$7.32M 0.5%
331,240
+19,450
+6% +$340K
CDNA icon
37
CareDx
CDNA
$2.35B
$6.99M 0.48%
221,663
-106,040
-32% -$3.09M
CHAC.U
38
DELISTED
Chardan Healthcare Acquisition Corp.
CHAC.U
$6.02M 0.41%
600,000
– –
IMDX
39
Insight Molecular Diagnostics
IMDX
$161M
$5.09M 0.35%
+64,444
New +$4.16M
VIVE
40
DELISTED
VIVEVE MED INC
VIVE
$4.21M 0.29%
4,481
– –
ARGX icon
41
argenx
ARGX
$54.3B
$3.83M 0.26%
30,714
+1,937
+7% +$228K
ECOR icon
42
electroCore
ECOR
$58.9M
$3.63M 0.25%
34,569
– –
STIM icon
43
Neuronetics
STIM
$164M
$2.54M 0.17%
166,561
-1,167
-0.7% -$19.3K
LJPC
44
DELISTED
La Jolla Pharmaceutical Company
LJPC
$1.94M 0.13%
301,166
+33,130
+12% +$216K
MOTS
45
DELISTED
Motus GI Holdings, Inc. Common Stock
MOTS
$1.79M 0.12%
1,532
– –
SLDB icon
46
Solid Biosciences
SLDB
$859M
$1.3M 0.09%
9,456
+556
+6% +$139K
VRAY
47
DELISTED
ViewRay, Inc.
VRAY
$1.18M 0.08%
159,247
-1,204,909
-88% -$9.29M
OPTN
48
DELISTED
OptiNose
OPTN
$851K 0.06%
5,510
+212
+4% +$24.6K
CMMB
49
Chemomab Therapeutics
CMMB
$12.8M
$411K 0.03%
+944
New +$477K
ASMB icon
50
Assembly Biosciences
ASMB
$526M
– –
-57,220
Closed -$15.5M
1
2
3

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RTW Investments's Q1 2019 Portfolio in Review

As of Q1 2019, RTW Investments held 55 positions worth $1.47B, up 34% from $1.09B the previous quarter. Its ten largest holdings account for 58% of the portfolio.

RTW Investments deployed $157M of net new capital in Q1 2019, opening 7 new positions and adding to 25 existing holdings. Its largest new stake was Wave Life Sciences: 436,777 shares worth $17M.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 92% a quarter earlier.

On the sell side, the largest reduction was Arrowhead Research, an estimated $62.5M trimmed.

  • RTW Investments's largest Q1 2019 buy was Wave Life Sciences: 436,777 shares worth $17M.
  • RTW Investments added most to ProQR Therapeutics in Q1 2019, an estimated $48.9M increase.
  • RTW Investments's biggest Q1 2019 reduction was Arrowhead Research, cutting an estimated $62.5M.
  • RTW Investments fully exited Sage Therapeutics in Q1 2019, selling an estimated $15.9M.
  • RTW Investments's ten largest holdings make up 58% of its $1.47B portfolio in Q1 2019.
  • RTW Investments opened 7 new positions and closed 4 in Q1 2019.
  • RTW Investments's portfolio value rose 34% quarter-over-quarter to $1.47B.

Based on RTW Investments's 13F filing for Q1 2019, filed 15 May 2019.