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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
-24.91%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$1.09B
AUM Growth
-$580M
Cap. Flow
-$124M
Cap. Flow %
-11.41%
Top 10 Hldgs %
62.53%
Holding
60
New
14
Increased
22
Reduced
10
Closed
12

Top Buys

Rank Stock Value
1
QTTB icon
Q32 Bio
QTTB
+$25.2M
2
ADVM
Adverum Biotechnologies
ADVM
+$24.7M
3
SAGE
Sage Therapeutics
SAGE
+$19M
4
RCKT icon
Rocket Pharmaceuticals
RCKT
+$17.7M
5
ASMB icon
Assembly Biosciences
ASMB
+$16.6M

Top Sells

Rank Stock Value
1
PRQR icon
ProQR Therapeutics
PRQR
+$60.4M
2
PTCT icon
PTC Therapeutics
PTCT
+$48.7M
3
CORI
Corium International, Inc.
CORI
+$34.3M
4
ARWR icon
Arrowhead Research
ARWR
+$31.3M
5
ILMN icon
Illumina
ILMN
+$30.3M

Sector Composition

Rank Sector Weight
1 Healthcare 91.62%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
QURE icon
26
uniQure
QURE
$3.03B
$13.3M 1.22%
461,837
+32,857
+8% +$914K
JNJ icon
27
Johnson & Johnson
JNJ
$614B
$10.4M 0.95%
+80,583
New +$11.2M
CNCE
28
DELISTED
Concert Pharmaceuticals, Inc.
CNCE
$9.9M 0.91%
+788,877
New +$10.9M
VRAY
29
DELISTED
ViewRay, Inc.
VRAY
$8.28M 0.76%
1,364,156
-2,025,342
-60% -$15.2M
CDNA icon
30
CareDx
CDNA
$2.44B
$8.24M 0.76%
327,703
-30,063
-8% -$772K
KIDS icon
31
OrthoPediatrics
KIDS
$536M
$7.85M 0.72%
+225,000
New +$7.13M
LAB icon
32
Standard BioTools
LAB
$321M
$7.62M 0.7%
+884,235
New +$6.89M
PRQR icon
33
ProQR Therapeutics
PRQR
$258M
$7.07M 0.65%
448,141
-3,291,265
-88% -$60.4M
CHAC.U
34
DELISTED
Chardan Healthcare Acquisition Corp.
CHAC.U
$6.04M 0.55%
+600,000
New +$6M
VIVE
35
DELISTED
VIVEVE MED INC
VIVE
$4.71M 0.43%
4,481
+1,334
+42% +$3.2M
ODT
36
DELISTED
Odonate Therapeutics, Inc. Common Stock
ODT
$4.39M 0.4%
311,790
+22,182
+8% +$345K
SLDB icon
37
Solid Biosciences
SLDB
$849M
$3.58M 0.33%
8,900
-8,588
-49% -$4.04M
STIM icon
38
Neuronetics
STIM
$160M
$3.25M 0.3%
167,728
+10,241
+7% +$225K
ECOR icon
39
electroCore
ECOR
$56.2M
$3.24M 0.3%
34,569
+257
+0.7% +$33.6K
ARGX icon
40
argenx
ARGX
$52.8B
$2.77M 0.25%
28,777
+1,924
+7% +$171K
LJPC
41
DELISTED
La Jolla Pharmaceutical Company
LJPC
$2.53M 0.23%
268,036
-929,071
-78% -$14M
MRTX
42
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
$1.64M 0.15%
+38,765
New +$1.54M
MOTS
43
DELISTED
Motus GI Holdings, Inc. Common Stock
MOTS
$1.43M 0.13%
1,532
+1,334
+674% +$1.48M
KA
44
DELISTED
Kineta, Inc. Common Stock
KA
$1.02M 0.09%
2,239
-5,826
-72% -$3.95M
LIVN icon
45
PUT
LivaNova
LIVN
$4.69B
$723K 0.07%
+7,900
New +$848K
OPTN
46
DELISTED
OptiNose
OPTN
$493K 0.05%
+5,298
New +$757K
VTAK icon
47
Catheter Precision
VTAK
$996K
– –
0
– –
ELDN icon
48
Eledon Pharmaceuticals
ELDN
$269M
– –
-17,570
Closed -$1.48M
ILMN icon
49
Illumina
ILMN
$30.7B
– –
-84,934
Closed -$30.3M
MRKR icon
50
Marker Therapeutics
MRKR
$20.5M
– –
-20,972
Closed -$1.9M
1
2
3

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IIM
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ACA
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FPAS
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RTW Investments's Q4 2018 Portfolio in Review

As of Q4 2018, RTW Investments held 60 positions worth $1.09B, down 35% from $1.67B the previous quarter. Its ten largest holdings account for 63% of the portfolio.

RTW Investments withdrew a net $124M in Q4 2018, closing 12 positions and reducing 10 holdings. Its most notable exit was Corium International, Inc., an estimated $34.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, down from 93% a quarter earlier.

Against the trend, RTW Investments opened a new position in Sage Therapeutics worth $15.9M.

  • RTW Investments's largest Q4 2018 buy was Sage Therapeutics: 165,990 shares worth $15.9M.
  • RTW Investments added most to Q32 Bio in Q4 2018, an estimated $25.2M increase.
  • RTW Investments's biggest Q4 2018 reduction was ProQR Therapeutics, cutting an estimated $60.4M.
  • RTW Investments fully exited Corium International, Inc. in Q4 2018, selling an estimated $34.3M.
  • RTW Investments's ten largest holdings make up 63% of its $1.09B portfolio in Q4 2018.
  • RTW Investments opened 14 new positions and closed 12 in Q4 2018.
  • RTW Investments's portfolio value fell 35% quarter-over-quarter to $1.09B.

Based on RTW Investments's 13F filing for Q4 2018, filed 14 Feb 2019.