Manulife (Manufacturers Life Insurance)’s Septerna, Inc. Common Stock SEPN Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2025 Q1	–	Sell	-22,095	Closed	-$506K	–	2999
2024 Q4	$506K	Buy	+22,095	New	+$506K	﹤0.01%	2235