HS
SEPN

HighVista Strategies’s Septerna Inc SEPN Stock Holding History

HighVista Strategies’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$982K Buy
+29,337
New +$832K 0.22% 118
2026
Q1 		– Sell
-78,682
Closed -$2.19M – 179
2025
Q4 		$2.19M Buy
+78,682
New +$1.88M 0.56% 50

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

HighVista Strategies's SEPN Position: Q2 2026 in Review

HighVista Strategies opened a new position in Septerna Inc (SEPN) in Q2 2026: 29,337 shares worth $982K. The stake represents 0.22% of the portfolio and ranks #118 among its holdings. This is a return to the name: HighVista Strategies previously reported a position in SEPN as recently as Q4 2025.

HighVista Strategies first reported a position in SEPN in Q4 2025 and has held it in 2 quarters since. The position peaked at $2.19M in Q4 2025. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • HighVista Strategies held 29,337 shares of Septerna Inc worth $982K as of Q2 2026.
  • Septerna Inc was a new HighVista Strategies position in Q2 2026.
  • Septerna Inc made up 0.22% of HighVista Strategies's portfolio in Q2 2026, its #118 holding.
  • HighVista Strategies first reported a position in Septerna Inc in Q4 2025 and has held it in 2 quarters since.
  • HighVista Strategies's Septerna Inc position peaked at $2.19M in Q4 2025.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on HighVista Strategies's 13F filing for Q2 2026, filed 14 Aug 2026.