FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $2.5B
1-Year Est. Return 52.94%
This Quarter Est. Return
1 Year Est. Return
+52.94%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$2.19B
AUM Growth
-$221M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
54
New
Increased
Reduced
Closed

Top Buys

1
+$45.5M
2
+$15.5M
3
+$15.1M
4
ZLAB icon
Zai Lab
ZLAB
+$12.6M
5
MIRM icon
Mirum Pharmaceuticals
MIRM
+$10.1M

Top Sells

1
+$63.1M
2
+$33.9M
3
+$20.8M
4
KRYS icon
Krystal Biotech
KRYS
+$18M
5
PLRX icon
Pliant Therapeutics
PLRX
+$14.8M

Sector Composition

1 Healthcare 99.79%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MREO
26
Mereo BioPharma
MREO
$317M
$17.6M 0.8%
7,819,863
+2,722,084
MRUS icon
27
Merus
MRUS
$7.19B
$15.7M 0.72%
373,100
RNA icon
28
Avidity Biosciences
RNA
$6.85B
$15.5M 0.71%
+525,000
HLVX
29
DELISTED
HilleVax
HLVX
$15.4M 0.7%
10,617,062
DYN icon
30
Dyne Therapeutics
DYN
$2.35B
$15.1M 0.69%
+1,443,341
ZLAB icon
31
Zai Lab
ZLAB
$3.14B
$12.6M 0.58%
+350,000
IMCR icon
32
Immunocore
IMCR
$1.71B
$8.94M 0.41%
301,170
+192,408
ORIC icon
33
Oric Pharmaceuticals
ORIC
$1.25B
$7.87M 0.36%
1,410,193
-2,478,045
ACAD icon
34
Acadia Pharmaceuticals
ACAD
$3.5B
$7.81M 0.36%
470,338
DSGN icon
35
Design Therapeutics
DSGN
$336M
$7.54M 0.34%
1,953,547
RCKT icon
36
Rocket Pharmaceuticals
RCKT
$397M
$7.2M 0.33%
1,079,025
-400,000
AUTL
37
Autolus Therapeutics
AUTL
$426M
$7.17M 0.33%
4,623,324
ORKA
38
Oruka Therapeutics
ORKA
$1.29B
$5.98M 0.27%
583,327
ALLO icon
39
Allogene Therapeutics
ALLO
$273M
$5.65M 0.26%
3,868,750
+1,001,000
IMTX icon
40
Immatics
IMTX
$1.23B
$5.63M 0.26%
1,247,911
-900,000
COGT icon
41
Cogent Biosciences
COGT
$2.28B
$5.61M 0.26%
936,576
ADVM icon
42
Adverum Biotechnologies
ADVM
$90.2M
$4.67M 0.21%
1,069,244
NAMSW icon
43
NewAmsterdam Pharma Warrant
NAMSW
$113M
$4.5M 0.21%
500,333
MGNX icon
44
MacroGenics
MGNX
$106M
$4.03M 0.18%
3,175,665
LXEO icon
45
Lexeo Therapeutics
LXEO
$472M
$3.32M 0.15%
955,515
SLN
46
Silence Therapeutics
SLN
$305M
$3.24M 0.15%
1,148,591
ELEV
47
DELISTED
Elevation Oncology
ELEV
$1.55M 0.07%
5,993,579
ANAB icon
48
AnaptysBio
ANAB
$928M
– –
-1,573,719
ARVN icon
49
Arvinas
ARVN
$684M
– –
-285,331
ETNB icon
50
89bio
ETNB
$2.19B
– –
-1,000,000
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