FLSM
Frazier Life Sciences Management Portfolio holdings
AUM
$2.5B
This Quarter Return
+2.24%
1 Year Return
+52.94%
3 Year Return
+530.54%
5 Year Return
–
10 Year Return
–
AUM
$2.19B
AUM Growth
+$2.19B
(-9.2%)
Cap. Flow
-$90.6M
Cap. Flow
% of AUM
-4.14%
Top 10 Holdings %
Top 10 Hldgs %
70.17%
Holding
54
New
4
Increased
10
Reduced
8
Closed
7
Top Buys
| 1 |
MAZE
Maze Therapeutics, Inc. Common Stock
MAZE
|
$45.5M |
| 2 |
Avidity Biosciences
RNA
|
$15.5M |
| 3 |
Dyne Therapeutics
DYN
|
$15.1M |
| 4 |
Zai Lab
ZLAB
|
$12.6M |
| 5 |
Mirum Pharmaceuticals
MIRM
|
$10.1M |
Top Sells
| 1 |
Rhythm Pharmaceuticals
RYTM
|
$63.1M |
| 2 |
Edgewise Therapeutics
EWTX
|
$33.9M |
| 3 |
AnaptysBio
ANAB
|
$20.8M |
| 4 |
Krystal Biotech
KRYS
|
$18M |
| 5 |
Pliant Therapeutics
PLRX
|
$14.8M |
Sector Composition
| 1 | Healthcare | 99.79% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
|
MREO
26
Mereo BioPharma
MREO
$272M
| $17.6M | 0.8% | 7,819,863 +2,722,084 | +53% | +$6.12M |
|
27
Merus
MRUS
$4.98B
| $15.7M | 0.72% | 373,100 | – | – |
|
|
28
Avidity Biosciences
RNA
$5.99B
| $15.5M | 0.71% | +525,000 | New | +$15.5M |
|
29
HilleVax
HLVX
$105M
| $15.4M | 0.7% | 10,617,062 | – | – |
|
|
30
Dyne Therapeutics
DYN
$1.92B
| $15.1M | 0.69% | +1,443,341 | New | +$15.1M |
|
|
31
Zai Lab
ZLAB
$3.68B
| $12.6M | 0.58% | +350,000 | New | +$12.6M |
|
32
Immunocore
IMCR
$1.62B
| $8.94M | 0.41% | 301,170 +192,408 | +177% | +$5.71M |
|
33
Oric Pharmaceuticals
ORIC
$994M
| $7.87M | 0.36% | 1,410,193 -2,478,045 | -64% | -$13.8M |
|
34
Acadia Pharmaceuticals
ACAD
$4.38B
| $7.81M | 0.36% | 470,338 | – | – |
|
35
Design Therapeutics
DSGN
$315M
| $7.54M | 0.34% | 1,953,547 | – | – |
|
36
Rocket Pharmaceuticals
RCKT
$354M
| $7.2M | 0.33% | 1,079,025 -400,000 | -27% | -$2.67M |
|
|
AUTL
37
Autolus Therapeutics
AUTL
$399M
| $7.17M | 0.33% | 4,623,324 | – | – |
|
|
ORKA
38
Oruka Therapeutics, Inc. Common Stock
ORKA
$554M
| $5.98M | 0.27% | 583,327 | – | – |
|
39
Allogene Therapeutics
ALLO
$251M
| $5.65M | 0.26% | 3,868,750 +1,001,000 | +35% | +$1.46M |
|
40
Immatics
IMTX
$619M
| $5.63M | 0.26% | 1,247,911 -900,000 | -42% | -$4.06M |
|
41
Cogent Biosciences
COGT
$1.69B
| $5.61M | 0.26% | 936,576 | – | – |
|
42
Adverum Biotechnologies
ADVM
$64.6M
| $4.67M | 0.21% | 1,069,244 | – | – |
|
43
NewAmsterdam Pharma Company N.V. Warrant
NAMSW
$58.3M
| $4.5M | 0.21% | 500,333 | – | – |
|
44
MacroGenics
MGNX
$112M
| $4.03M | 0.18% | 3,175,665 | – | – |
|
45
Lexeo Therapeutics
LXEO
$259M
| $3.32M | 0.15% | 955,515 | – | – |
|
|
SLN
46
Silence Therapeutics
SLN
$227M
| $3.24M | 0.15% | 1,148,591 | – | – |
|
|
ELEV
47
DELISTED
Elevation Oncology
ELEV
| $1.55M | 0.07% | 5,993,579 | – | – |
|
48
Day One Biopharmaceuticals
DAWN
$769M
| – | – | -689,655 | Closed | -$8.74M |
|
49
Eledon Pharmaceuticals
ELDN
$155M
| – | – | -1,176,735 | Closed | -$4.85M |
|
|
50
AnaptysBio
ANAB
$569M
| – | – | -1,573,719 | Closed | -$20.8M |
|