FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $2.5B
This Quarter Return
-1.92%
1 Year Return
+52.94%
3 Year Return
+530.54%
5 Year Return
–
10 Year Return
–
AUM
$1.38B
AUM Growth
+$1.38B
Cap. Flow
-$62.1M
Cap. Flow %
-4.5%
Top 10 Hldgs %
65.28%
Holding
52
New
8
Increased
7
Reduced
4
Closed
3

Top Buys

1
BBIO icon
BridgeBio Pharma
BBIO
$19.4M
2
RVMD icon
Revolution Medicines
RVMD
$18.5M
3
ELVN icon
Enliven Therapeutics
ELVN
$18.2M
4
MGNX icon
MacroGenics
MGNX
$12.2M
5
MORF
Morphic Holding, Inc. Common Stock
MORF
$8.06M

Top Sells

1
IMGO
Imago BioSciences, Inc. Common stock
IMGO
$143M
2
ALLK
Allakos
ALLK
$16.4M
3
KRYS icon
Krystal Biotech
KRYS
$4.35M
4
REPL icon
Replimune Group
REPL
$4.32M
5
EPIX icon
ESSA Pharma
EPIX
$1.52M

Sector Composition

1 Healthcare 99.93%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TRVI icon
26
Trevi Therapeutics
TRVI
$871M
$12.3M 0.89%
6,663,590
– –
MGNX icon
27
MacroGenics
MGNX
$121M
$12.2M 0.88%
+1,703,204
New +$12.2M
REPL icon
28
Replimune Group
REPL
$460M
$12.1M 0.88%
686,762
-244,798
-26% -$4.32M
VECT
29
DELISTED
VectivBio Holding AG Ordinary Shares
VECT
$11.6M 0.84%
1,352,199
+18,799
+1% +$162K
CERE
30
DELISTED
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
$9.59M 0.69%
393,000
– –
IMVT icon
31
Immunovant
IMVT
$2.91B
$9.09M 0.66%
585,759
– –
STRO icon
32
Sutro Biopharma
STRO
$85.6M
$8.21M 0.59%
1,776,479
– –
MORF
33
DELISTED
Morphic Holding, Inc. Common Stock
MORF
$8.06M 0.58%
+214,240
New +$8.06M
ARVN icon
34
Arvinas
ARVN
$580M
$7.8M 0.56%
285,331
– –
RNA icon
35
Avidity Biosciences
RNA
$6.12B
$7.68M 0.56%
500,000
– –
NTLA icon
36
Intellia Therapeutics
NTLA
$1.26B
$7.59M 0.55%
203,684
– –
AUTL
37
Autolus Therapeutics
AUTL
$383M
$6.89M 0.5%
3,746,857
– –
JBIO
38
Jade Biosciences, Inc. Common Stock
JBIO
$245M
$6.82M 0.49%
+9,660
New +$6.82M
PRTA icon
39
Prothena Corp
PRTA
$452M
$6.2M 0.45%
127,900
– –
ZYME icon
40
Zymeworks
ZYME
$1.07B
$5.51M 0.4%
610,000
– –
SLN
41
Silence Therapeutics
SLN
$237M
$5.46M 0.4%
881,173
– –
ALLK
42
DELISTED
Allakos
ALLK
$4.95M 0.36%
1,112,684
-3,679,316
-77% -$16.4M
BLUE
43
DELISTED
bluebird bio
BLUE
$4.58M 0.33%
72,038
– –
EWTX icon
44
Edgewise Therapeutics
EWTX
$1.54B
$4.55M 0.33%
+682,461
New +$4.55M
PASG icon
45
Passage Bio
PASG
$22.7M
$3.6M 0.26%
187,846
– –
ADCT icon
46
ADC Therapeutics
ADCT
$370M
$3.21M 0.23%
+1,647,030
New +$3.21M
ACRS icon
47
Aclaris Therapeutics
ACRS
$223M
$2.14M 0.15%
264,377
-25,812
-9% -$209K
NAMSW icon
48
NewAmsterdam Pharma Company N.V. Warrant
NAMSW
$64M
$921K 0.07%
500,333
– –
NBRV
49
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$29.7K ﹤0.01%
17,025
– –
EPIX icon
50
ESSA Pharma
EPIX
$11.2M
– –
-605,141
Closed -$1.52M
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