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FLSM

Frazier Life Sciences Management Portfolio holdings

AUM $3.89B
1-Year Est. Return 201.1%
This Fund
S&P 500
This Quarter Est. Return
+37.43%
1 Year Est. Return
+201.1%
3 Year Est. Return
+879.31%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$1.3B
AUM Growth
+$239M
Cap. Flow
+$108M
Cap. Flow %
8.34%
Top 10 Hldgs %
67.1%
Holding
47
New
6
Increased
10
Reduced
7
Closed
4

Top Buys

1
RYTM icon
Rhythm Pharmaceuticals
RYTM
+$35.2M
2
PHAT icon
Phathom Pharmaceuticals
PHAT
+$24.6M
3
ALLK
Allakos
ALLK
+$20.1M
4
VRNA
Verona Pharma
VRNA
+$17.7M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
+$13.9M

Top Sells

1
SRRA
Sierra Oncology, Inc. Common Stock
SRRA
+$47.9M
2
VRDN icon
Viridian Therapeutics
VRDN
+$11.3M
3
PCVX icon
Vaxcyte
PCVX
+$6.08M
4
KRYS icon
Krystal Biotech
KRYS
+$5.56M
5
PASG icon
Passage Bio
PASG
+$2.47M

Sector Composition

1 Healthcare 98.83%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TYRA icon
26
Tyra Biosciences
TYRA
$1.87B
$11.7M 0.9%
1,327,665
-47,400
-3% -$434K
NTLA icon
27
Intellia Therapeutics
NTLA
$1.64B
$11.4M 0.88%
203,684
– –
CERE
28
DELISTED
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
$11.1M 0.86%
393,000
+190,740
+94% +$5.68M
STRO icon
29
Sutro Biopharma
STRO
$395M
$9.86M 0.76%
177,648
– –
GRCL
30
DELISTED
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$9.31M 0.72%
2,890,102
-221,449
-7% -$720K
BLUE
31
DELISTED
bluebird bio
BLUE
$9.12M 0.7%
+72,038
New +$8.15M
SLN
32
Silence Therapeutics
SLN
$496M
$8.7M 0.67%
881,173
– –
TRVI icon
33
Trevi Therapeutics
TRVI
$2.43B
$8.32M 0.64%
5,403,590
+4,231,963
+361% +$13.9M
AUTL
34
Autolus Therapeutics
AUTL
$394M
$8.02M 0.62%
3,746,857
– –
ACRS icon
35
Aclaris Therapeutics
ACRS
$740M
$6.43M 0.49%
408,329
– –
PASG icon
36
Passage Bio
PASG
$16.1M
$4.7M 0.36%
187,846
-62,615
-25% -$2.47M
IMVT icon
37
Immunovant
IMVT
$7.94B
$3.27M 0.25%
585,759
– –
MGNX icon
38
MacroGenics
MGNX
$257M
$2.43M 0.19%
+701,631
New +$2.68M
PRDS
39
DELISTED
Pardes Biosciences, Inc. Common Stock
PRDS
$1.56M 0.12%
845,636
– –
EPIX
40
DELISTED
ESSA Pharma
EPIX
$1.26M 0.1%
692,910
– –
MTEM
41
DELISTED
Molecular Templates, Inc.
MTEM
$1.03M 0.08%
91,603
– –
APTX
42
DELISTED
Aptinyx Inc. Common Stock
APTX
$693K 0.05%
1,883,244
– –
NBRV
43
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$35K ﹤0.01%
17,025
-1
-0% -$4
VRDN icon
44
Viridian Therapeutics
VRDN
$1.97B
– –
-980,302
Closed -$11.3M
ISEE
45
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
– –
-170,000
Closed -$1.64M
EPZM
46
DELISTED
Epizyme, Inc
EPZM
– –
-739,369
Closed -$1.09M
SRRA
47
DELISTED
Sierra Oncology, Inc. Common Stock
SRRA
– –
-870,636
Closed -$47.9M
1
2

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